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New treatment option for Endometriosis
Official title The Role of Probiotics in the Treatment of Endometriosis (ProMetrioS): a Randomised Double-blinded Placebo-controlled Cross-over Trial
ClinicalTrials.gov ID: NCT06929364
What this study is testing
- What it's testing
- ProMetrioS is a randomised blinded placebo-controlled cross-over trial investigating the effect of specific multistrain probiotics in patients with endometriosis. The aim of this clinical trial is to determine whether probiotic treatment can significantly modulate gut microbiome composition and functionality in endometriosis patients, specifically parameters associated with the estrobolome.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages up to 35, women only
You may be able to join if
- Minimum Age: - Maximum Age: 35 Years Sex: Female Gender Based: Ye - only women can participate in this study Accepts Healthy Volunteers: No
- adult people with stage III or IV endometriosis diagnosis confirmed by biopsy
You likely can't join if
- Age \> 35 years
- Immunocompromised patients
- Patients with chronic inflammatory diseases (e.g., autoimmune disorders)
- Pregnancy
- Use of supplements and foods with probiotics
- Use of immunosuppressant, antibiotic, proton pump inhibitors and corticosteroid drugs
See the full eligibility criteria
- Minimum Age: - Maximum Age: 35 Years Sex: Female Gender Based: Ye - only women can participate in this study Accepts Healthy Volunteers: No
- adult people with stage III or IV endometriosis diagnosis confirmed by biopsy
- Age \> 35 years
- Immunocompromised patients
- Patients with chronic inflammatory diseases (e.g., autoimmune disorders)
- Pregnancy
- Use of supplements and foods with probiotics
- Use of immunosuppressant, antibiotic, proton pump inhibitors and corticosteroid drugs
- Use of probiotics product less than one month before start of study or during study
The study team makes the final eligibility decision.
Where it's taking place
- Zagreb, Croatia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, up to 35 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Zagreb, Croatia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.