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New treatment option for Lymphoma
Official title Interrupting Sedentary Time to Improve Cardiometabolic Health and Toxicity in Patients With Lymphoma Receiving Chemotherapy: The iSTAND Trial
ClinicalTrials.gov ID: NCT06923397
What this study is testing
- What it's testing
- This study aims to see if a 12-week exercise program designed to reduce long periods of inactivity is feasible in newly diagnosed lymphoma participants receiving R-CHOP or POLA-R-CHP chemotherapy treatments, and whether it can improve heart health and reduce chemotherapy drug side effects.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Ability to understand and the willingness to sign informed consent prior to any study- related procedures.
- Patients diagnosed with lymphoma.
- Will receive first line R-CHOP or POLA-R-CHP chemotherapy regimens, patients do not need to be within a certain timeframe from diagnosis.
- Aged ≥18 years; due to the rarity of the disease in those \<18 years, this age bracket will not be included.
- Engaging in ≤60-minutes of structured moderate or vigorous intensity exercise.
You likely can't join if
- Unstable comorbidities that prevent participation in moderate-to-vigorous intensity exercise. Patients with unstable comorbidities likely require...
- Participate in more than 60 minutes of structured moderate-to-vigorous exercise per week over the last month. Excess additional exercise is a...
- Patients receiving treatment for other active malignancies (except basal cell carcinoma). This study is exclusively targeting lymphoma...
- Patients currently taking weight loss drugs.
- people who in the opinion of the investigators may not be able to comply with the safety monitoring requirements of the study.
- Unable to travel to DFCI Longwood campus for necessary data collection and chemotherapy infusions.
See the full eligibility criteria
- Ability to understand and the willingness to sign informed consent prior to any study- related procedures.
- Patients diagnosed with lymphoma.
- Will receive first line R-CHOP or POLA-R-CHP chemotherapy regimens, patients do not need to be within a certain timeframe from diagnosis.
- Aged ≥18 years; due to the rarity of the disease in those \<18 years, this age bracket will not be included.
- Engaging in ≤60-minutes of structured moderate or vigorous intensity exercise.
- Have physician clearance to participate in exercise.
- Speak English.
- Willing to travel to Dana-Farber Cancer Institute for necessary data collection and exercise sessions.
- Access to a phone that can receive text messages.
- Unstable comorbidities that prevent participation in moderate-to-vigorous intensity exercise. Patients with unstable comorbidities likely require supervised exercise for safety, and part of this study involves...
- Participate in more than 60 minutes of structured moderate-to-vigorous exercise per week over the last month. Excess additional exercise is a confounding factor in assessing the effect of the current interrupted...
- Patients receiving treatment for other active malignancies (except basal cell carcinoma). This study is exclusively targeting lymphoma chemotherapy-related effects.
- Patients currently taking weight loss drugs.
- people who in the opinion of the investigators may not be able to comply with the safety monitoring requirements of the study.
- Unable to travel to DFCI Longwood campus for necessary data collection and chemotherapy infusions.
The study team makes the final eligibility decision.
Where it's taking place
- Boston, Massachusetts, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Boston, Massachusetts, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.