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New treatment option for Lung Cancer (NSCLC)
Official title Ultrasound-guided Cryobiopsy of Mediastinal/Hilar Lymph Nodes
ClinicalTrials.gov ID: NCT06921681
What this study is testing
- What it's testing
- EBUS-guided cryobiopsy of mediastinal and hilar lymph nodes has shown to be a useful diagnostic tool to obtain tissue for histological analysis and further targeted therapies in lung malignancies. Due to the large size and better quality of the tissue samples, a higher diagnostic yield than with transbronchial needle aspiration (TBNA) can be expected, especially in non-solid tumors.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 90
You may be able to join if
- At least one mediastinal lesion or hilar 1 cm or longer in the short axis requiring diagnostic bronchoscopy
- Age between 18 and 90 years
- Written informed consent after participant's information
You likely can't join if
- Age \ 90 years
- Lacking ability to form an informed consent (including impaired judgement, communication barriers)
- Contraindication against bronchoscopy (e.g. co-morbidities)
- Mediastinal abscess or cyst
- Extraordinary blood supply of the lesion visualized by EBUS bronchoscope
- INR \> 1.5 or Thrombocytes \< 100 G/l
See the full eligibility criteria
- At least one mediastinal lesion or hilar 1 cm or longer in the short axis requiring diagnostic bronchoscopy
- Age between 18 and 90 years
- Written informed consent after participant's information
- Age \ 90 years
- Lacking ability to form an informed consent (including impaired judgement, communication barriers)
- Contraindication against bronchoscopy (e.g. co-morbidities)
- Mediastinal abscess or cyst
- Extraordinary blood supply of the lesion visualized by EBUS bronchoscope
- INR \> 1.5 or Thrombocytes \< 100 G/l
- Clopidogrel or other new antiplatelet drugs within 7 days before biopsy (salicylic acid alone allowed)
- Anticoagulation with NOAC within 48 hours before biopsy
- Pulmonary lesions suspicious of lung carcinoma
The study team makes the final eligibility decision.
Where it's taking place
- Basel, Switzerland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Basel, Switzerland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.