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New treatment option for Dientamoeba Fragilis Infection
Official title Paromomycin or Metronidazole for Symptomatic Dientamoeba Fragilis in Adults
ClinicalTrials.gov ID: NCT06907498
What this study is testing
What is Paromomycin?
Paromomycin is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for dientamoeba fragilis infection.
Also referred to as Kaman.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Dientameba Fragilis (D.fragilis) is a protozoan found in the digestive tract - in the human colon. there are disagreements regarding the preferred treatment for these cases, with several regimens tested in mostly small observational studies.
- Time commitment: about 3 months
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patients over the age of 18, not including pregnant women - With persistent gastrointestinal symptoms (over one month).
- Without any other clear diagnosis to explain these symptoms according to medical records.
- With a positive PCR stool test for D. fragilis without any additional pathogen (patients with Blastocystis hominis in feces will not be excluded).
You likely can't join if
- Pregnancy
- Hypersensitivity to any of the study drugs or to aminoglycosides
- Patients age below 18 years
- Metronidazole or paromomycin treatment in the last 3 months
The study team makes the final eligibility decision.
Where it's taking place
- Ramat Gan, Israel, Israel
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 3 months per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ramat Gan, Israel, Israel. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.