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New treatment option for Nociceptive Pain
Official title Guiding Opioid Administration by Nociception Level Index (NOL) in Patients With Regional Anesthesia
ClinicalTrials.gov ID: NCT06905340
What this study is testing
- What it's testing
- General anesthesia consists of a combination of hypnotic drugs to achieve unconsciousness and opioid analgesics to ensure antinociception. An alternative approach to the intraoperative administration of high-potency opioids to achieve antinociception during surgery is combining general anesthesia with regional anesthesia.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- \- Patients undergoing elective trauma or orthopedic surgery with a combination of general and regional anesthesia
You likely can't join if
- Preexisting therapy with cardiac glycosides or pacemakers
- Cardiac arrhythmia (atrial fibrillation, atrioventricular block \> I°)
- Chronic opioid misuse
- Intraoperative treatment with ketamine, beta-adrenergic agonists, or clonidine
- Serious peripheral or cardiac autonomic neuropathy
- Inability to specify the postoperative pain level
See the full eligibility criteria
- \- Patients undergoing elective trauma or orthopedic surgery with a combination of general and regional anesthesia
- Preexisting therapy with cardiac glycosides or pacemakers
- Cardiac arrhythmia (atrial fibrillation, atrioventricular block \> I°)
- Chronic opioid misuse
- Intraoperative treatment with ketamine, beta-adrenergic agonists, or clonidine
- Serious peripheral or cardiac autonomic neuropathy
- Inability to specify the postoperative pain level
- Postoperative treatment in an ICU
The study team makes the final eligibility decision.
Where it's taking place
- Hamburg, Germany
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hamburg, Germany. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.