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Official title Effect of Daily Mixed Spice Consumption on Memory Function
ClinicalTrials.gov ID: NCT06889961
What this study is testing
- What it's testing
- The aging process entails a multitude of structural and functional alterations within the brain, culminating in a gradual and progressive decline in cognitive function. Recent research has indicated that various spices may hold the key to enhancing brain health and combating the effects of aging on cognitive abilities.
- Time commitment: about 3 months
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 to 80. Healthy volunteers may be eligible.
You may be able to join if
- Participants are required to have clinical histories consistent with normal aging or mild cognitive impairment (MCI).
- Age 50 to 80 years.
- Adequate visual acuity and hearing to allow neuropsychological testing.
- Screening laboratory tests without significant abnormalities that might interfere with the study. \-
You likely can't join if
- Diagnosis of probable Alzheimer's disease or any other dementia (e.g. vascular, Lewy body, frontotemporal)
- Evidence of other neurological or physical illness that can produce cognitive deterioration. Determination of dementia will be based on the clinical...
- Evidence of Parkinson's disease as determined by the motor examination (items 18-31) of the Unified Parkinson's Disease Rating Scale [38].
- Uncontrolled hypertension (systolic blood pressure (BP) \> 170 or diastolic BP \> 100).
- Consume spices regularly \> 5g day
- Allergy or sensitivity to spices. people will be excluded if there is a prior history of such sensitivity. Since these foods are commonly eaten and...
See the full eligibility criteria
- Participants are required to have clinical histories consistent with normal aging or mild cognitive impairment (MCI).
- Age 50 to 80 years.
- Adequate visual acuity and hearing to allow neuropsychological testing.
- Screening laboratory tests without significant abnormalities that might interfere with the study. \-
- Diagnosis of probable Alzheimer's disease or any other dementia (e.g. vascular, Lewy body, frontotemporal)
- Evidence of other neurological or physical illness that can produce cognitive deterioration. Determination of dementia will be based on the clinical evaluation including assessment of functional abilities, and cognitive...
- Evidence of Parkinson's disease as determined by the motor examination (items 18-31) of the Unified Parkinson's Disease Rating Scale [38].
- Uncontrolled hypertension (systolic blood pressure (BP) \> 170 or diastolic BP \> 100).
- Consume spices regularly \> 5g day
- Allergy or sensitivity to spices. people will be excluded if there is a prior history of such sensitivity. Since these foods are commonly eaten and allergies are rare, people should be aware of this sensitivity prior to...
- Current diagnosis of any major psychiatric disorder according to the DSM-IV TR criteria (APA, 2000).
- Current diagnosis or alcoholism or substance addiction.
- Eating a high fiber/polyphenol diet or taking any medication or dietary supplement which interfere with the absorption of polyphenols.
- Frequently using prebiotics, probiotics, yogurt, and/or any fiber supplements
The study team makes the final eligibility decision.
Where it's taking place
- Los Angeles, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 3 months per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years to 80 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Los Angeles, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.