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New treatment option for Cognitive Disorders
Official title Dietary Strategy to Tackle Cognitive and Locomotor Abilities in Early Elderly Subjects
ClinicalTrials.gov ID: NCT06871384
What this study is testing
- What it's testing
- Polyphenols, precisely resveratrol, with red wine as the most substantial source, was associated with improvements in cognitive function. Also, the loss of muscle mass and strength in elderly, that significantly increases dependency of these people, it could be attributed to alterations in gut microbiota through the "gut-muscle axis" and this underline the urgent need to efficiently find out any intervention or preventive approach via modulation of gut microbiota to improve muscle function in elderly.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 to 74. Healthy volunteers may be eligible.
You may be able to join if
- 1\. Men or women between 60-74 years old; Sensory tolerance to red wine; Written informed consent provided before the initial screening visit.
You likely can't join if
- Men or women \>75 years old,
- Hypoglucaemiant treatment or type 1 and type 2 diabetes mellitus diagnosed
- Anaemia (hemoglobin ≤13 g/dL in men and ≤12 g/dL in women)
- people diagnosed of intestinal disorders such as chron disease, colitis ulcerous, and irritable bowel syndrome
- To present a clinical active chronic disease
- To present severe sarcopenia
See the full eligibility criteria
- 1\. Men or women between 60-74 years old; Sensory tolerance to red wine; Written informed consent provided before the initial screening visit.
- Men or women \>75 years old,
- Hypoglucaemiant treatment or type 1 and type 2 diabetes mellitus diagnosed
- Anaemia (hemoglobin ≤13 g/dL in men and ≤12 g/dL in women)
- people diagnosed of intestinal disorders such as chron disease, colitis ulcerous, and irritable bowel syndrome
- To present a clinical active chronic disease
- To present severe sarcopenia
- To present cognitive impairment (MMSE ≤ 24 or clinical diagnosis of mild cognitive impairment or dementia)
- Dietary allergies to: Mediterranean foods (eg, nuts), sulphytes or nitrates
- Use of antioxidants supplements
- Regular consumers of red wine who do not agree to change the consumption of red wine with alcohol to nonalcholized wine during the intervention
- Chronic alcoholism
- Current or past participation in a clinical trial or consumption of a research product in the 30 days prior to inclusion in the study
- Failure to follow the study guidelines. For participation in the muscle biopsy, additional exclusion criteria included: Use of prescription anti-platelet medication; Prescription anticoagulant use (or antiaggregant, or...
The study team makes the final eligibility decision.
Where it's taking place
- Logroño, Spain, Spain
- Reus, Spain, Spain
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years to 74 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Logroño, Spain, Spain; Reus, Spain, Spain. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.