BridgeMD
New treatment option for Idiopathic Rhinitis
Official title Posterior Nasal Nerve Combined with Anterior Ethmoid Neurotomy for Idiopathic Rhinitis
ClinicalTrials.gov ID: NCT06870292
What this study is testing
What is Drug therapy group?
Drug therapy group is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for idiopathic rhinitis.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The present study was a randomised, parallel controlled, open-label, multicentre clinical study. The trial was divided into two groups, the posterior nasal nerve combined with anterior ethmoid neurotomy group (group A) and the conventional drug treatment group (group B).
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Patients signed the free and informed consent form and understood the explanation of the study.
- patients with IR between 18 and 65 years and their body mass index (BMI) should be ≥19 kg/m2 and ≤24 kg/m2.
- Patients diagnosed with idiopathic rhinitis （IR）that were defined as nonsmoking patients with at least 2 nasal complaints of nasal obstruction...
- Patients with negative skin prick test (SPT) responses or sIgE
- Nasal cytological exam with eosinophilia less than 20%.
You likely can't join if
- Patients with colored secretions, inflammation，nasal polyps, chronic sinusitis, nasal tumours.
- Patients with other chronic rhinitis such as occupational rhinitis, drug rhinitis, gustatory rhinitis, hormonal rhinitis, atrophic rhinitis, etc.
- Patients with anatomic nasal abnormalities responsible for nasal symptoms.
- Patients with nasal/sinus surgery 3 months before the study.
- Patients with severe mental illness.
- Patients with uncontrolled asthma, systemic disorders or malignancies.
See the full eligibility criteria
- Patients signed the free and informed consent form and understood the explanation of the study.
- patients with IR between 18 and 65 years and their body mass index (BMI) should be ≥19 kg/m2 and ≤24 kg/m2.
- Patients diagnosed with idiopathic rhinitis （IR）that were defined as nonsmoking patients with at least 2 nasal complaints of nasal obstruction, rhinorrhea, itching, and/or sneezing for more than 1 hour a day and for...
- Patients with negative skin prick test (SPT) responses or sIgE
- Nasal cytological exam with eosinophilia less than 20%.
- Patients had a Total Nasal Symptom Score (TNSS) of ≥6 and a subscore of nasal discharge ≥2 and a subscore of nasal congestion ≥1.
- Patients with colored secretions, inflammation，nasal polyps, chronic sinusitis, nasal tumours.
- Patients with other chronic rhinitis such as occupational rhinitis, drug rhinitis, gustatory rhinitis, hormonal rhinitis, atrophic rhinitis, etc.
- Patients with anatomic nasal abnormalities responsible for nasal symptoms.
- Patients with nasal/sinus surgery 3 months before the study.
- Patients with severe mental illness.
- Patients with uncontrolled asthma, systemic disorders or malignancies.
- Patients with history of chronic smoking, substance abuse, drug use, and/or excessive alcohol consumption.
- Patients in pregnancy or lactation.
The study team makes the final eligibility decision.
Where it's taking place
- Wuhan, Hubei, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Wuhan, Hubei, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.