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New treatment option for Osteoporosis in Post-menopausal Women
Official title A Clinical Study on the Effect of Discontinuing Alendronate in Postmenopausal Women With Osteoporosis After a Treatment Period Without Fractures
ClinicalTrials.gov ID: NCT06864130
What this study is testing
What is Alendronate 70mg weekly?
Alendronate 70mg weekly is an investigational medicine, given as an once-weekly, being studied as a potential treatment for osteoporosis in post-menopausal women.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to study the effects of discontinuation of Alendronate treatment for three years. The participants are postmenopausal women with osteoporosis, who have had a treatment period without fractures.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Adults, women only
You may be able to join if
- Female
- Postmenopausal
- Current treatment with Alendronate
- Alendronate treatment \>3 år AND no fracture OR
- Alendronate treatment \>5 år AND latest low energy fracture \> 3 years ago
You likely can't join if
- T-score \< - 3,5 in hip (total hip or femoral neck) or lumbar spine
- Treatment with systemic glucocorticoids, ongoing or within 12 months
- Uncontrolled inflammatory disease
- Active malignancy
- eGFR \< 40 mL/min
- Atypical femur fracture (ever)
See the full eligibility criteria
- Female
- Postmenopausal
- Current treatment with Alendronate
- Alendronate treatment \>3 år AND no fracture OR
- Alendronate treatment \>5 år AND latest low energy fracture \> 3 years ago
- T-score \< - 3,5 in hip (total hip or femoral neck) or lumbar spine
- Treatment with systemic glucocorticoids, ongoing or within 12 months
- Uncontrolled inflammatory disease
- Active malignancy
- eGFR \< 40 mL/min
- Atypical femur fracture (ever)
- OsteoNecrosis of the Jaw (active)
- Unable to give inform consent
The study team makes the final eligibility decision.
Where it's taking place
- Aalborg, Denmark
- Copenhagen, Denmark
- Esbjerg, Denmark
- Herlev, Denmark
- Hillerød, Denmark
- Hvidovre, Denmark
- Odense, Denmark
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, not specified. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Aalborg, Denmark; Copenhagen, Denmark; Esbjerg, Denmark; Herlev, Denmark; Hillerød, Denmark; Hvidovre, Denmark and 1 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.