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New treatment option for Dissection Carotid Artery
Official title Next Generation Sequencing Analysis of Patients with Spontaneous Dissection of Cervical Arteries
ClinicalTrials.gov ID: NCT06862063
What this study is testing
- What it's testing
- The goal of this observational study is to analyze the existence of a genetic predisposition in patients with spontaneous dissections of the cervical arteries (SCeAD). The main questions it aims to answer are: 1.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult age (≥18 years);
- Presence of a dissection of one or more cervical arteries (carotid or vertebrobasilar district), defined as the finding, on an appropriate...
- At least one or more of the following criteria:
- Radiological evidence on CT and/or MRI with/without contrast and/or digital subtraction angiography and/or color Doppler ultrasound of vessel wall...
- Family history of:
You likely can't join if
- Recent history of trauma clearly related in type, location and dynamics to the development of dissection;
- Iatrogenic dissection following endovascular procedure;
- Exclusively intracranial dissection;
- Fibromuscular dysplasia.
See the full eligibility criteria
- Adult age (≥18 years);
- Presence of a dissection of one or more cervical arteries (carotid or vertebrobasilar district), defined as the finding, on an appropriate radiological examination (CT and/or MRI of the neck and brain district...
- At least one or more of the following criteria:
- Radiological evidence on CT and/or MRI with/without contrast and/or digital subtraction angiography and/or color Doppler ultrasound of vessel wall anomalies (such as aneurysms, dissections, tortuosity, ectasia or...
- Family history of:
- vessel dissections and/or sudden death and/or cerebrovascular or cardiovascular diseases at a young age;
- spontaneous perforation of internal organs and/or dehiscence and/or laxity of connective tissue (spontaneous prolapses);
- dysmorphological abnormalities at the clinical examination (including Beighton score ≥5 or Marfan score ≥7), laboratory and/or radiological findings suggestive of connective tissue disease or other genetic condition...
- Written informed consent
- Recent history of trauma clearly related in type, location and dynamics to the development of dissection;
- Iatrogenic dissection following endovascular procedure;
- Exclusively intracranial dissection;
- Fibromuscular dysplasia.
The study team makes the final eligibility decision.
Where it's taking place
- Rome, Lazio, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Rome, Lazio, Italy. Enter your location above to see the nearest site and check your eligibility.
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BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.