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Tests treatment safety and results for Preoperative Anxiety
Official title Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General Anesthesia
ClinicalTrials.gov ID: NCT06853431
What this study is testing
What is dexmedetomidine?
dexmedetomidine is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for preoperative anxiety.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- For pediatric patients undergoing general anesthesia, poor anesthesia induction compliance often has adverse effects on individual behavior in the early postoperative period. Dexmedetomidine can reduce the cardiovascular responses and postoperative mental adverse reactions caused by esketamine anesthesia induction [6].
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 12 to 72
You may be able to join if
- ASA physical status classification Grade I or II;
- Age 1-6 years old;
- Children who need to undergo general anesthesia for elective surgery;
- Weight within the normal range;
- Signed informed consent form. -
You likely can't join if
- The child's guardian or the child themselves refuses to participate in the study;
- Patients with contraindications for sedation/anesthesia or a history of abnormal recovery from sedation/anesthesia;
- Individuals known to be allergic to the study drugs, opioid drugs, or rescue medications;
- Individuals with a history of heart, brain, liver, kidney, or metabolic diseases;
- Individuals with an upper respiratory tract infection within the past two weeks;
- Individuals with other diseases that may cause harm to the subject. -
The study team makes the final eligibility decision.
Where it's taking place
- Wenzhou, Zhejiang, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 12 months to 72 months. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Wenzhou, Zhejiang, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.