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New treatment option for Idiopathic Pulmonary Fibrosis
Official title Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis
ClinicalTrials.gov ID: NCT06853145
What this study is testing
What is Hyperpolarized Xe129?
Hyperpolarized Xe129 is an investigational medicine, being studied as a potential treatment for idiopathic pulmonary fibrosis.
Also referred to as 129 HXe MRI.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Idiopathic pulmonary fibrosis has a poor prognosis with limited treatment options. The Investigator hypothesize hyperpolarized Xe129-MRI can be performed in patients with IPF and repeated over time which will detect deficiencies related to perfusion in the lung.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Able to provide informed consent 18 years of age or greater Clinical diagnosis of IPF
You likely can't join if
- Continuous oxygen use at home
- Oxygen saturation less than 92% on the day of MRI procedure
- Pregnancy or lactation
- Claustrophobia, inner ear implants, aneurysm or other surgical clips, metal foreign bodies in eye, pacemaker or other contraindication to MR...
- History of congenital cardiac disease, chronic renal failure, or cirrhosis. Chest circumference greater than that of the xenon MR and/or helium coil...
- Inability to understand simple instructions or to hold still for approximately 10-15 seconds.
See the full eligibility criteria
- Able to provide informed consent 18 years of age or greater Clinical diagnosis of IPF
- Continuous oxygen use at home
- Oxygen saturation less than 92% on the day of MRI procedure
- Pregnancy or lactation
- Claustrophobia, inner ear implants, aneurysm or other surgical clips, metal foreign bodies in eye, pacemaker or other contraindication to MR scanning. people with any implanted device that cannot be verified as MRI...
- History of congenital cardiac disease, chronic renal failure, or cirrhosis. Chest circumference greater than that of the xenon MR and/or helium coil. The circumference of the coil is approximately 42 inches.
- Inability to understand simple instructions or to hold still for approximately 10-15 seconds.
- History of respiratory infection within 2 weeks prior to the MR scan
- History of MI, stroke and/or poorly controlled hypertension.
The study team makes the final eligibility decision.
Where it's taking place
- Charlottesville, Virginia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Charlottesville, Virginia, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.