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New treatment option for Traumatic Brain Injury
Official title Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain Injury
ClinicalTrials.gov ID: NCT06848140
What this study is testing
- What it's testing
- The purpose of this study is to learn more about how brain stimulation affects word finding problems in people who have a traumatic brain injury (TBI). The type of brain stimulation used is called transcranial direct current stimulation (tDCS).
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 85
You may be able to join if
- Age between 18 and 85
- Fluent in speaking and reading English
- Able to provide informed consent
- Has a TBI at least one year prior to enrollment and not related to military experience
- Has a confirmation of verbal retrieval difficulties as measured by the Verbal Retrieval Difficulty Interview questions
You likely can't join if
- Lifetime major or active neurologic conditions (e.g., stroke, epilepsy, brain tumor, dementia, seizure occurrence less than one year ago)
- Lifetime major or active cardiovascular conditions (e.g., cardiac arrythmia, heart failure, heart attack)
- Current substance use disorder
- Lifetime major psychiatric disorders (e.g., schizophrenia, bipolar disorder)
- Severe depression at the time of enrollment (BDI-II \>= 29) or psychiatric ER visits or hospitalization less than 6 months ago prior to enrollment
- Current sensory (e.g., blind, deaf) or physical (e.g., severe motor weakness) impairment that interferes with testing
See the full eligibility criteria
- Age between 18 and 85
- Fluent in speaking and reading English
- Able to provide informed consent
- Has a TBI at least one year prior to enrollment and not related to military experience
- Has a confirmation of verbal retrieval difficulties as measured by the Verbal Retrieval Difficulty Interview questions
- Lifetime major or active neurologic conditions (e.g., stroke, epilepsy, brain tumor, dementia, seizure occurrence less than one year ago)
- Lifetime major or active cardiovascular conditions (e.g., cardiac arrythmia, heart failure, heart attack)
- Current substance use disorder
- Lifetime major psychiatric disorders (e.g., schizophrenia, bipolar disorder)
- Severe depression at the time of enrollment (BDI-II \>= 29) or psychiatric ER visits or hospitalization less than 6 months ago prior to enrollment
- Current sensory (e.g., blind, deaf) or physical (e.g., severe motor weakness) impairment that interferes with testing
- Contraindications for tDCS or MRI
- The person cannot be left alone for 8+ hours.
- Not verbally communicative.
- Currently undergoing and not wishing to discontinue speech and cognitive therapy during study participation.
- Incapable of understanding the consent or unable to consent for oneself.
- Unable to travel to BIDMC's Berenson-Allen Center
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Boston, Massachusetts, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Boston, Massachusetts, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.