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Prevention study for To Evaluate the Safety of Taurine in Preventing Acute Radiation Skin...
Official title Phase I-II Clinical Study of Taurine for External Use in the Prevention and Treatment of Acute Radiation Skin Injury
ClinicalTrials.gov ID: NCT06847555
What this study is testing
- What it's testing
- Acute radiation skin injury is the most common side effect of radiation therapy in patients with chest tumors, which can be manifested as erythema, dry peeling, wet peeling, and severe ulcers. Even with current advanced radiotherapy techniques, such as intensity-modulated reverse radiation therapy (IMRT), about one-third of patients develop grade 2 or higher skin damage during radiotherapy.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older, women only
You may be able to join if
- Breast cancer patients scheduled for conventional fractionated adjuvant
- radiotherapy.
- 18 years or older
- ECOG score 0-1
- No previous history of other neoplasms.
You likely can't join if
- Pregnant or lactating women, women in childbearing years who do not use effective contraception；
- Patients with mental disease or nervous system disease, unable to clearly describe treatment response (such as cerebrovascular accident sequela);
- Those who have serious heart, liver, kidney and other organ diseases or diabetes and are not expected to complete the treatment plan;
- serious, uncontrolled diseases and infections;
- Pregnant or lactating patients.
- Allergic to taurine and any of its components.
See the full eligibility criteria
- Breast cancer patients scheduled for conventional fractionated adjuvant
- radiotherapy.
- 18 years or older
- ECOG score 0-1
- No previous history of other neoplasms.
- No previous chest radiotherapy.
- Heart, lung function, liver function and kidney function were within normal range.
- Voluntary informed consent.
- Pregnant or lactating women, women in childbearing years who do not use effective contraception；
- Patients with mental disease or nervous system disease, unable to clearly describe treatment response (such as cerebrovascular accident sequela);
- Those who have serious heart, liver, kidney and other organ diseases or diabetes and are not expected to complete the treatment plan;
- serious, uncontrolled diseases and infections;
- Pregnant or lactating patients.
- Allergic to taurine and any of its components.
- Has participated in other clinical trials.
- knot tissue disease
- active hepatitis
- Obvious diseases that the investigator considers should be excluded from this study
The study team makes the final eligibility decision.
Where it's taking place
- Jinan, Shandong, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Jinan, Shandong, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.