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New treatment option for Proteinuric Kidney Disease
Official title A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
ClinicalTrials.gov ID: NCT06830629
What this study is testing
What is MZE829?
MZE829 is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for proteinuric kidney disease.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 68
You may be able to join if
- APOL1 high risk genotype of G1/G1, G2/G2, or G1/G2
- Chronic kidney disease with persistent albuminuria Key
You likely can't join if
- Organ or bone marrow transplantation
- History of cancer within past 2 years, excepted for treated non-melanoma skin cancer, stage 0 cervical cancer, or stage 1 prostate cancer
- Conditions that may alter drug absorption, e.g., history of bariatric surgery
- Type I diabetes
- Pregnant or currently nursing Other inclusion/exclusion criteria defined in protocol apply.
The study team makes the final eligibility decision.
Where it's taking place
- Decatur, Alabama, United States
- Huntsville, Alabama, United States
- Montgomery, Alabama, United States
- Granada Hills, California, United States
- Bloomfield, Connecticut, United States
- Atlantis, Florida, United States
- Brandon, Florida, United States
- Brooksville, Florida, United States
- Hollywood, Florida, United States
- Melbourne, Florida, United States
- Miami Lakes, Florida, United States
- Orlando, Florida, United States
- Atlanta, Georgia, United States
- College Park, Georgia, United States
- Cordele, Georgia, United States
- Lithia Springs, Georgia, United States
- Macon, Georgia, United States
- Riverdale, Georgia, United States
- Savannah, Georgia, United States
- Snellville, Georgia, United States
+ 49 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 68 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Decatur, Alabama, United States; Huntsville, Alabama, United States; Montgomery, Alabama, United States; Granada Hills, California, United States; Bloomfield, Connecticut, United States; Atlantis, Florida, United States and 63 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.