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New treatment option for Hypoxemic Acute Respiratory Failure
Official title Closed Loop Oxygen Control in INtubated Critically Ill Patients
ClinicalTrials.gov ID: NCT06829732
What this study is testing
- What it's testing
- The deleterious effects of alveolar hyperoxia and (severe) hyperoxaemia are well described. Achieving safe and efficient oxygenation may be challenging.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patients admitted to the ICU who are expected to require invasive mechanical ventilation for at least 8 hours and are expected to stay respiratory...
- Acute respiratory failure with PaO2/FiO2 \<300 with FiO2 ≥ 0.4 at inclusion
- Age older than 18 years old.
- Written informed consent signed and dated by the patient or one relative in case that the patient is unable to consent, after full explanation of the...
You likely can't join if
- Low quality on the SpO2 measurement using finger and ear sensor (quality index \<60%).
- Hemodynamic instability defined as a need of continuous infusion of epinephrine or norepinephrine \> 1 mg/h.
- Severe acidosis (pH ≤ 7.30).
- Chronic or acute dyshemoglobinemia: methemoglobin, CO poisoning, sickle cell disease.
- Patient under guardianship or deprived of liberties.
- Impossibility to give informed consent by both patient and family (i.e. language barrier).
See the full eligibility criteria
- Patients admitted to the ICU who are expected to require invasive mechanical ventilation for at least 8 hours and are expected to stay respiratory stable´ in the upcoming 8 hours.
- Acute respiratory failure with PaO2/FiO2 \<300 with FiO2 ≥ 0.4 at inclusion
- Age older than 18 years old.
- Written informed consent signed and dated by the patient or one relative in case that the patient is unable to consent, after full explanation of the study by the investigator and prior to study participation.
- Low quality on the SpO2 measurement using finger and ear sensor (quality index \<60%).
- Hemodynamic instability defined as a need of continuous infusion of epinephrine or norepinephrine \> 1 mg/h.
- Severe acidosis (pH ≤ 7.30).
- Chronic or acute dyshemoglobinemia: methemoglobin, CO poisoning, sickle cell disease.
- Patient under guardianship or deprived of liberties.
- Impossibility to give informed consent by both patient and family (i.e. language barrier).
- Patient included in another treatment research study under consent with similar outcome.
The study team makes the final eligibility decision.
Where it's taking place
- Sabadell, Barcelona, Spain
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Sabadell, Barcelona, Spain. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.