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New treatment option for Lung Transplant Rejection
Official title Cryoprobe Biopsy and Chronic Rejection in Lung Transplant Recipients
ClinicalTrials.gov ID: NCT06824402
What this study is testing
- What it's testing
- The goal of this clinical trial is to evaluate which biopsy collection method helps to better diagnose rejection and relevant pathologic findings in lung transplant recipients. The main questions it aims to answer are: Does the 1.1 mm cryoprobe or the biopsy forceps provide better quality samples of lung tissue for detecting rejection in transplant recipients?
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 99
You may be able to join if
- Male and female lung transplant recipients age \>18 at the time of informed consent
- Patients clinically meet indication for post-transplant lung biopsy or planned routine surveillance and have been scheduled for bronchoscopy with...
- Be willing and able to sign the informed consent.
You likely can't join if
- Patients with known bleeding diathesis
- Platelet count \<50,000 per μL within 14 days of the biopsy procedure
- Current use of systemic anticoagulation or antiplatelet therapy without the ability to hold therapy for the recommended amount of time prior to an...
- Inability or unwillingness to give informed consent or study procedures
- Pregnant or nursing females, or females who intend to become pregnant
- Females of child-bearing potential who decline a pregnancy test prior to enrollment
See the full eligibility criteria
- Male and female lung transplant recipients age \>18 at the time of informed consent
- Patients clinically meet indication for post-transplant lung biopsy or planned routine surveillance and have been scheduled for bronchoscopy with transbronchial biopsy.
- Be willing and able to sign the informed consent.
- Patients with known bleeding diathesis
- Platelet count \<50,000 per μL within 14 days of the biopsy procedure
- Current use of systemic anticoagulation or antiplatelet therapy without the ability to hold therapy for the recommended amount of time prior to an invasive procedure (aspirin monotherapy is acceptable)
- Inability or unwillingness to give informed consent or study procedures
- Pregnant or nursing females, or females who intend to become pregnant
- Females of child-bearing potential who decline a pregnancy test prior to enrollment
- If an investigator does not feel that this study is in the subject's best interest or would be a good fit for the study.
- International Normalized Ratio (INR) \>1.5
- Do Not Resuscitate (DNR) status
- Do Not Intubate (DNI) status
- Single lung transplant recipients
The study team makes the final eligibility decision.
Where it's taking place
- Rochester, Minnesota, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 99 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Rochester, Minnesota, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.