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Compares treatment options for Post-Dural Puncture Headache
Official title Comparison of Nebulized Neostigmine/Atropine Versus Lignocaine in Treating Acute Post-dural Puncture Headache Following Subarachnoid Block in Parturient Undergoing Elective Cesarean Section. A Randomized, Clinical Trial.
ClinicalTrials.gov ID: NCT06824025
What this study is testing
What is lidocaine group ( nebulized lidocaine + saline) total volume 4 ml?
lidocaine group ( nebulized lidocaine + saline) total volume 4 ml is an investigational medicine, given as an inhaled treatment, being studied as a potential treatment for post-dural puncture headache.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Post-dural puncture headache (PDPH) is a common and debilitating complication of spinal anesthesia in pregnant patients undergoing cesarean sections, with an incidence ranging from 0.5% to 2% (1). The International Headache Society (IHS) defines PDPH as a headache occurring within 4 days of a lumbar puncture, caused by cerebrospinal fluid (CSF) leakage through the dural puncture (2).
- Phase 1: an early, usually small safety study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 35, women only
You may be able to join if
- 18-35 years old parturient with post partum headache after elective CS under spinal anesthesia with visual analog score (VAS) ≥ 4 [14] and Lybecker...
You likely can't join if
- Pregnancy induced hypertension
- Emergency C.S
- Asthmatic candidates
- Previous history of migraine or trigeminal neuralgia
- History of bronchial asthma
- Post partum hemorrhage
See the full eligibility criteria
- 18-35 years old parturient with post partum headache after elective CS under spinal anesthesia with visual analog score (VAS) ≥ 4 [14] and Lybecker classification score ≥ 2
- Pregnancy induced hypertension
- Emergency C.S
- Asthmatic candidates
- Previous history of migraine or trigeminal neuralgia
- History of bronchial asthma
- Post partum hemorrhage
- Need for GA , failed spinal anesthesia
- Patient refusal
The study team makes the final eligibility decision.
Where it's taking place
- Minya, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 35 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Minya, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.