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New treatment option for Chronic Pain Patients
Official title Medical Cannabis and Behavior
ClinicalTrials.gov ID: NCT06808048
What this study is testing
- What it's testing
- This study will assess cognition, neural function, and drug exposure in chronic pain patients who have been prescribed medical cannabis and will differentiate outcomes based on use of specific CBD-dominant versus THC-dominant treatment products. This longitudinal study will recruit medical cannabis users from local dispensaries.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 30 to 75
You may be able to join if
- Medical cannabis users (n=120) will be required to
- Be ages 30-75;
- Be qualified for a medical cannabis prescription based only on a diagnosis of chronic pain; note that individuals can, in theory, utilize medical...
- Have normal or corrected-to-normal vision and hearing;
- Be free of current and past DSM-V-defined substance use disorders; have \< 5 lifetime recreational uses of illicit drugs.
You likely can't join if
- Cannot have a degenerative neurological condition or a neurological condition that impacts brain function (e.g., epilepsy);
- No contraindications to MRI scanning;
- No lifetime history of severe DSM-V psychopathology (psychotic disorders, bipolar disorder); if currently treated mood for anxiety disorders, must be...
- No current pregnancy or pregnancy within the prior 3 months; cannot be lactating;
See the full eligibility criteria
- Medical cannabis users (n=120) will be required to
- Be ages 30-75;
- Be qualified for a medical cannabis prescription based only on a diagnosis of chronic pain; note that individuals can, in theory, utilize medical cannabis for more than one qualifying condition. People with orthopedic...
- Have normal or corrected-to-normal vision and hearing;
- Be free of current and past DSM-V-defined substance use disorders; have \< 5 lifetime recreational uses of illicit drugs.
- Have limited daily exposure to nicotine (e.g., no daily smokers/vapers; use of nicotine products fewer than 5 occasions weekly);
- Willing to abstain from alcohol, nicotine, and other (non-treatment) drugs for 24 hours prior to study. Abstinence will be verified by breathalyzer and urine drug screening; must not test positive on breathalyzer and...
- Must be right handed as assessed by the Edinburgh Handedness Inventory;
- No history of daily cannabis use; limited cannabis product use (recreational or therapeutic) within the past three months;
- Able to schedule and complete a multi-hour single session protocol;
- Have sufficient manual mobility to be able to complete computerized neurocognitive assessments;
- Able to communicate with the researchers by phone during the four month pre-post assessment interval Pain patients who are not using medical cannabis (n=60) will be required to:
- Be ages 30-75;
- Suffer from a chronic pain condition that could qualify them for medical cannabis; People with orthopedic pain will be prioritized.
- Have normal or corrected-to-normal vision and hearing;
- Be free of current and past DSM-V-defined substance use disorders; have \< 5 lifetime recreational uses of illicit drugs.
- Have limited daily exposure to nicotine (e.g., no daily smokers/vapers; use of nicotine products fewer than 5 occasions weekly);
- Willing to abstain from alcohol, nicotine, and other (non-treatment) drugs for 24 hours prior to study. Abstinence will be verified by breathalyzer and urine drug screening; must not test positive on breathalyzer and...
- Must be right handed as assessed by the Edinburgh Handedness Inventory;
- No history of daily cannabis use; cannabis use within the past three months limited to a few times.
- Able to schedule and complete a multi-hour single session protocol;
- Have sufficient manual mobility to be able to complete computerized neurocognitive assessments;
- Able to communicate with the researchers by phone during the four month pre-post assessment interval Within both groups, concomitant opioid use will be allowed as will other prescribed treatments. Controls will be...
- Cannot have a degenerative neurological condition or a neurological condition that impacts brain function (e.g., epilepsy);
- No contraindications to MRI scanning;
- No lifetime history of severe DSM-V psychopathology (psychotic disorders, bipolar disorder); if currently treated mood for anxiety disorders, must be stable;
- No current pregnancy or pregnancy within the prior 3 months; cannot be lactating;
The study team makes the final eligibility decision.
Where it's taking place
- Minneapolis, Minnesota, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 30 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Minneapolis, Minnesota, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.