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New treatment option for Coronary Arterial Disease (CAD)
Official title Prolonged Chest Tube Treatment to Reduce Rates of Atrial Fibrillation Following Cardiac Surgery
ClinicalTrials.gov ID: NCT06800781
What this study is testing
- What it's testing
- Evacuation of pericardial blood by posterior pericardiotomy or use of a posterior pericardial chest tube lowers postoperative atrial fibrillation (POAF) rates after cardiac surgery by 45-68%. Although it cannot be generalized due to trial undersizing, posterior pericardial chest tube treatment may be a superior alternative to pericardiotomy, given its low risk of procedural complications.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥ 18 years
- Undergoing non-emergent surgery (\>24 hours between decision to operate and surgical procedure) with coronary artery bypass grafting, aortic valve...
- Able to give written informed consent
You likely can't join if
- History of atrial fibrillation (AF) or atrial flutter
- History of electrophysiological interventions or treatment with antiarrhythmic drugs due to arrhythmias other than AF
- Pre- or postoperative prophylactic treatment with amiodarone
- Existing pacemaker, ICD, or CRT device without a functional atrial lead
- Aortic surgery with hypothermic circulatory arrest
- Previous cardiac surgery
See the full eligibility criteria
- Age ≥ 18 years
- Undergoing non-emergent surgery (\>24 hours between decision to operate and surgical procedure) with coronary artery bypass grafting, aortic valve replacement, aortic surgery without the use of circulatory arrest, or...
- Able to give written informed consent
- History of atrial fibrillation (AF) or atrial flutter
- History of electrophysiological interventions or treatment with antiarrhythmic drugs due to arrhythmias other than AF
- Pre- or postoperative prophylactic treatment with amiodarone
- Existing pacemaker, ICD, or CRT device without a functional atrial lead
- Aortic surgery with hypothermic circulatory arrest
- Previous cardiac surgery
- Previous radiation of the chest due to malignancy
- Ongoing infection at time of surgery
- Ongoing treatment with immunosuppressants, including oral corticosteroids
- Patient already included in another treatment clinical trial
- Patient listed abroad, which would render them to be lost to follow-up after discharge
- Patient does not understand study information given in the local language or, for other reasons, is deemed unfit to participate according to the investigators.
The study team makes the final eligibility decision.
Where it's taking place
- Lund, Sweden
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Lund, Sweden. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.