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New treatment option for Peridontal Disease
Official title Assessment of Pro-Resolution Mediator Levels in Periodontitis Stage III and IV Before and After Periodontal Therapy
ClinicalTrials.gov ID: NCT06789458
What this study is testing
- What it's testing
- This study aims to assess Pro-Resolution Mediator levels during non-surgical periodontal therapy in individuals with Stage III and IV periodontitis, comparing them to healthy subjects. Periodontitis, a chronic inflammatory condition affecting tooth-supporting tissues, can lead to tooth loss and systemic complications.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Adult patients above 18 years old.
- Interdental CAL at site of greatest loss ≥5 mm or extending to middle third of the root.
- Interdental CAL at site of greatest loss ≥8 mm or extending to apical third of the root.
- Probing depth ≥6 mm.
- Vertical bone loss ≥3 mm.
You likely can't join if
- 1\. Pregnancy or lactation. 2. Smoking more than 20 cigarettes. 3. Immuno-inflammatory conditions of the skin and oral mucosa 4. systemic conditions...
- Systemically healthy patients.
- Patients with an age range between 16 to 80 years.
- Patients have a minimum of 20 teeth.
- Less than 10% bleeding sites with probing depths ≤3 mm.
- absence of erythema, oedema.
See the full eligibility criteria
- Adult patients above 18 years old.
- Interdental CAL at site of greatest loss ≥5 mm or extending to middle third of the root.
- Interdental CAL at site of greatest loss ≥8 mm or extending to apical third of the root.
- Probing depth ≥6 mm.
- Vertical bone loss ≥3 mm.
- Tooth loss due to periodontitis of ≤4 teeth. (Periodontitis Stage III)
- Tooth loss due to periodontitis of ≥5 teeth. (Periodontitis Stage IV)
- Furcation involvement Class II or III Moderate ridge defect. \-
- 1\. Pregnancy or lactation. 2. Smoking more than 20 cigarettes. 3. Immuno-inflammatory conditions of the skin and oral mucosa 4. systemic conditions affecting bone turnover and periodontal health status (e.g. endocrine...
- Systemically healthy patients.
- Patients with an age range between 16 to 80 years.
- Patients have a minimum of 20 teeth.
- Less than 10% bleeding sites with probing depths ≤3 mm.
- absence of erythema, oedema.
The study team makes the final eligibility decision.
Where it's taking place
- Manial, Cairo Governorate, Egypt
- Cairo, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Manial, Cairo Governorate, Egypt; Cairo, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.