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Compares treatment options for Acute Postoperative Pain
Official title Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty
ClinicalTrials.gov ID: NCT06784882
What this study is testing
What is single injection nerve block?
single injection nerve block is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for acute postoperative pain.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This is a single-center pilot study to determine if an adductor canal continuous nerve block is superior to single injection nerve block following total knee arthroplasty. Investigators will randomize participants to either continuous nerve block or single injection nerve block for the adductor canal preoperatively.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult participants of at least 18 years of age
- Undergoing a primary, unilateral, total knee arthroplasty
- Planned single-injection adductor canal nerve block
- Weight \> 50 kg (to minimize the risk of local anesthetic toxicity)
You likely can't join if
- chronic opioid or tramadol use: daily oxycodone equivalents \> 20 mg for \> 4 weeks
- neuro-muscular deficit of the surgical limb
- moderate pain (NRS \> 3) in an anatomic location other than the surgical site
- planned hospital admission following surgery
- history of opioid misuse
- those who lack capacity to complete informed consent
See the full eligibility criteria
- Adult participants of at least 18 years of age
- Undergoing a primary, unilateral, total knee arthroplasty
- Planned single-injection adductor canal nerve block
- Weight \> 50 kg (to minimize the risk of local anesthetic toxicity)
- chronic opioid or tramadol use: daily oxycodone equivalents \> 20 mg for \> 4 weeks
- neuro-muscular deficit of the surgical limb
- moderate pain (NRS \> 3) in an anatomic location other than the surgical site
- planned hospital admission following surgery
- history of opioid misuse
- those who lack capacity to complete informed consent
- inability to contact the investigators during the treatment period, and vice versa (e.g., lack of telephone access)
- incarceration
- pregnancy
- allergy to amide local anesthetics
The study team makes the final eligibility decision.
Where it's taking place
- La Jolla, California, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include La Jolla, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.