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Prevention study for Fecal Microbiota Transplantation
Official title Fecal Microbiota Transplantation for the Prevention of Infectious Complications After Liver Transplantation
ClinicalTrials.gov ID: NCT06782880
What this study is testing
- What it's testing
- The increasing emergence and spread of MDRB represents a major public health problem, with higher mortality in patients experiencing infections. Cirrhotic patients listed for OLT and after OLT are at high risk of MDRB colonization or infection due to the large use of broad-spectrum antibiotics in the post-transplant setting.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- Adult (age≥18 years) patients listed for OLT for various etiologies.
- Patient's consent to participate in the study
You likely can't join if
- Previous total colectomy
- Pregnancy or breastfeeding
- Patients on oral or intravenous antimicrobial agents
- HIV positive and not well controlled on antiretroviral therapy, or CD4+ \<200/ mm3
- Active SARS-CoV-2 infection
- Neutropenia \<0.5X10\^9/L
See the full eligibility criteria
- Adult (age≥18 years) patients listed for OLT for various etiologies.
- Patient's consent to participate in the study
- Previous total colectomy
- Pregnancy or breastfeeding
- Patients on oral or intravenous antimicrobial agents
- HIV positive and not well controlled on antiretroviral therapy, or CD4+ \<200/ mm3
- Active SARS-CoV-2 infection
- Neutropenia \<0.5X10\^9/L
- Toxic megacolon
- Contraindications to colonoscopy
- Any conditions for which, according to the physician, FMT endangers the patient's health
- History of hypersensitivity to macrogol contained in bowel preparations.
The study team makes the final eligibility decision.
Where it's taking place
- Bologna, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bologna, Italy. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.