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New treatment option for Endothelial Cell Loss, Corneal
Official title Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts
ClinicalTrials.gov ID: NCT06781970
What this study is testing
What is Oral Vitamin C?
Oral Vitamin C is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for endothelial cell loss, corneal.
Also referred to as ascorbic acid.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to analyze the protective effects of oral ascorbic acid on the corneal endothelial layer undergoing oxidative stress due to phacoemulsification in patients with hard cataracts. The main questions it aims to answer are: 1.
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 and older
You may be able to join if
- Males and females aged 60 years or older
- Patients with immature senile cataracts in one or both eyes, with LOC (lens opacities classification) III nuclear opacity grade 4-6 and nuclear color...
- Patients willing to undergo phacoemulsification cataract surgery and consume the study medication as allocated, as well as participate in follow-up...
- Patients with no history of previous intraocular surgery
- Patients with no history of allergy to vitamin C
See the full eligibility criteria
- Males and females aged 60 years or older
- Patients with immature senile cataracts in one or both eyes, with LOC (lens opacities classification) III nuclear opacity grade 4-6 and nuclear color grade 4-6 criteria
- Patients willing to undergo phacoemulsification cataract surgery and consume the study medication as allocated, as well as participate in follow-up assessments for 7 weeks
- Patients with no history of previous intraocular surgery
- Patients with no history of allergy to vitamin C
- Patients not routinely consuming other vitamins
- Patients who agree to and sign the informed consent for the study
The study team makes the final eligibility decision.
Where it's taking place
- Jakarta, DKI Jakarta, Indonesia
- Cianjur, West Java, Indonesia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Jakarta, DKI Jakarta, Indonesia; Cianjur, West Java, Indonesia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.