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New treatment option for Sleep Wake Disorders
Official title Clinical Study of Perioperative Sleep Disorders in Cardiac Surgery
ClinicalTrials.gov ID: NCT06778811
What this study is testing
What is Intraoperative infusion of dexmedetomidine?
Intraoperative infusion of dexmedetomidine is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for sleep wake disorders.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The aim of this clinical trial is to understand the effects of dexmedetomidine and esketamine on postoperative sleep in patients undergoing cardiac surgery. The main questions it aims to answer are: Does dexmedetomidine or esketamine prevent the development of postoperative sleep disturbances?
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 to 75
You may be able to join if
- ASA class II-III, NYHA class I-III, EF ≥ 50%
- Intended to perform cardiac surgery under extracorporeal circulation
You likely can't join if
- Patients undergoing second heart surgery
- Patients with mental retardation, deafness, or other conditions that interfere with normal communication
- Previous neurological or psychiatric disorders
- Patients with a history of sleep disorders
- Alcoholics, drug addicts, or psychotropic substance abusers
- Significant hepatic or renal dysfunction affecting drug metabolism
See the full eligibility criteria
- ASA class II-III, NYHA class I-III, EF ≥ 50%
- Intended to perform cardiac surgery under extracorporeal circulation
- Patients undergoing second heart surgery
- Patients with mental retardation, deafness, or other conditions that interfere with normal communication
- Previous neurological or psychiatric disorders
- Patients with a history of sleep disorders
- Alcoholics, drug addicts, or psychotropic substance abusers
- Significant hepatic or renal dysfunction affecting drug metabolism
- Contraindication to the use of dexmedetomidine or esketamine.
The study team makes the final eligibility decision.
Where it's taking place
- Nanjing, Jiangsu, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Nanjing, Jiangsu, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.