New treatment option for Borderline Personality Disorder
Official title Cognitive Reappraisal Training for Borderline Personality (BPD)
ClinicalTrials.gov ID: NCT06772831
What this study is testing
- What it's testing
- Previous work by the group convinced the researchers to pursue development of focused cognitive reappraisal training as a novel approach to treatment of BPD, either as stand-alone treatment or in concert with evidence-based treatments of BPD. The present proposal aims to refine and test a proposed clinical intervention for BPD patients, training in reappraisal-by-distancing, in terms of its ability to influence hypothesized neural and behavioral targets and, once that is established, to demonstrate its ability improve clinically relevant outcome measures.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 55
You may be able to join if
- Medically healthy men and women with Borderline Personality Disorder who are mentally competent and give informed voluntary written consent.
- Participants will be between the ages of 18 and 55.
- Within these requirements, the inclusion and
You likely can't join if
- do not reflect participation based on gender or racial/ethnic group. The targeted/planned enrollment is a reflection of previous recruitment of...
- Participants with comorbid avoidant personality disorder will be included.
- Participants who meet criteria for PTSD will be included as long as they are not actively experiencing symptoms. Exclusion Criteria:
- Participants will not meet criteria for Schizotypal Personality Disorder.
- Participants currently meeting criteria for Major Depressive Disorder will be excluded.
- BPD participants will not meet DSM-5 criteria for present PTSD, bipolar I disorder, schizophrenia, schizoaffective disorder, substance use disorder...
See the full eligibility criteria
- Medically healthy men and women with Borderline Personality Disorder who are mentally competent and give informed voluntary written consent.
- Participants will be between the ages of 18 and 55.
- Within these requirements, the inclusion and
- do not reflect participation based on gender or racial/ethnic group. The targeted/planned enrollment is a reflection of previous recruitment of female and ethnic minorities in other studies conducted by the PI and their...
- Participants with comorbid avoidant personality disorder will be included.
- Participants who meet criteria for PTSD will be included as long as they are not actively experiencing symptoms. Exclusion Criteria:
- Participants will not meet criteria for Schizotypal Personality Disorder.
- Participants currently meeting criteria for Major Depressive Disorder will be excluded.
- BPD participants will not meet DSM-5 criteria for present PTSD, bipolar I disorder, schizophrenia, schizoaffective disorder, substance use disorder within the past 6 months, organic mental syndromes, head trauma...
- Participants currently meeting criteria for major depressive disorder.
- Participants meeting criteria for substance use disorder within the last 6 months or of an IV-substance use disorder at any time.
- Participants may not have a pacemaker, surgical clips, any metallic implants, or shrapnel fragments that would contraindicate MRI scanning.
- Pregnant women.
The study team makes the final eligibility decision.
Where it's taking place
- New York, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 55 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include New York, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.