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New treatment option for Decompensated Liver Cirrhosis
Official title Statin and Beta Blocker Use in Patients With Decompensated Cirrhosis
ClinicalTrials.gov ID: NCT06764966
What this study is testing
What is Atorvastatin 20 mg?
Atorvastatin 20 mg is an investigational medicine, given as an once-daily, being studied as a potential treatment for decompensated liver cirrhosis.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Decompensated cirrhosis (liver disease) occurs when liver function decreases to the extent that serious complications develop and can include internal bleeding, fluid buildup in the abdomen, or mental confusion. This reduced decreased liver function subsequently decreases life expectancy.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patients age of 18 years or older diagnosed with any form of decompensated liver disease defined as ascites, hepatic encephalopathy, or variceal...
- Currently on an non-selective beta-blockers agreeing to have their liver disease managed by CAMC-Gastroenterology Liver Clinic as an outpatient for...
You likely can't join if
- Any patient \<18 years of age
- Patients with hepatocellular carcinoma
- Patients with ongoing alcohol use (self-reported consumption of more than one alcoholic drink per week)
- Patients exhibiting high-risk behaviors that could put them at risk for complications including IV substance use and history of medication...
- Patients currently on statin therapy
- Patients with a history of statin intolerance
See the full eligibility criteria
- Patients age of 18 years or older diagnosed with any form of decompensated liver disease defined as ascites, hepatic encephalopathy, or variceal bleed presenting at Charleston Area Medical Center (CAMC) Memorial...
- Currently on an non-selective beta-blockers agreeing to have their liver disease managed by CAMC-Gastroenterology Liver Clinic as an outpatient for the 12-month follow-up period.
- Any patient \<18 years of age
- Patients with hepatocellular carcinoma
- Patients with ongoing alcohol use (self-reported consumption of more than one alcoholic drink per week)
- Patients exhibiting high-risk behaviors that could put them at risk for complications including IV substance use and history of medication non-adherence
- Patients currently on statin therapy
- Patients with a history of statin intolerance
- Patients on the waitlist for liver transplantation
- Patients taking medications with known drug interactions with statins
- Patients not able to give informed consent or patients belonging to vulnerable categories as the Federal Regulations or Common Rule
The study team makes the final eligibility decision.
Where it's taking place
- Charleston, West Virginia, United States
Compensation & support
A stipend or compensation may be offered.
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Charleston, West Virginia, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.