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New treatment option for Heart Failure
Official title Effects of Low-Sodium Salt on Death, HF Hospitalization/ Emergency Department Visits and Quality of Life in HF Patients
ClinicalTrials.gov ID: NCT06764225
What this study is testing
- What it's testing
- This study aims to investigate whether using a low-sodium substitute salt can help improve outcomes for patients with heart failure. Specifically, it will examine if the low-sodium substitute salt can reduce death rates, hospital readmissions, and emergency visits, as well as improve the quality of life for these patients.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- Aged between 18 and 75 years;
- Hospitalized due to heart failure in the past year;
- NYHA functional class II-III;
- Echocardiographic evidence of LVEF \< 40% within the past 6 months;
- Receiving guideline-directed medical therapy for heart failure;
You likely can't join if
- End-stage heart failure;
- Hospitalization due to cardiovascular causes within the past month;
- Uncorrected hyponatremia (Na \< 130 mmol/L);
- Dialysis-dependent patients, or eGFR \< 20 mL/min/1.73m²;
- Uncontrolled hyperglycemia, with fasting blood glucose \> 16 mmol/L;
- Malignant cancer patients with a life expectancy of less than 1 year;
See the full eligibility criteria
- Aged between 18 and 75 years;
- Hospitalized due to heart failure in the past year;
- NYHA functional class II-III;
- Echocardiographic evidence of LVEF \< 40% within the past 6 months;
- Receiving guideline-directed medical therapy for heart failure;
- Stable heart failure status, defined as heart failure stability for more than 4 weeks, with no increase in diuretic dose within the past 4 weeks;
- Having a primary caregiver and frequently dining together at home;
- Consuming commercially processed food no more than once a week;
- Providing written informed consent.
- End-stage heart failure;
- Hospitalization due to cardiovascular causes within the past month;
- Uncorrected hyponatremia (Na \< 130 mmol/L);
- Dialysis-dependent patients, or eGFR \< 20 mL/min/1.73m²;
- Uncontrolled hyperglycemia, with fasting blood glucose \> 16 mmol/L;
- Malignant cancer patients with a life expectancy of less than 1 year;
- Conditions that, in the investigator's opinion, may interfere with adherence to the protocol, such as habitual reliance on takeout meals or dining at company cafeterias;
- Planned hospitalization during the study period;
- Unexplained weight loss greater than 5 kg in the past year;
- The subject or family members have concerns about using the salt substitute in this study, or are planning for pregnancy, pregnant, or breastfeeding;
- Another family member is already participating in this study;
- The subject or family members are participating in other treatment clinical trials.
The study team makes the final eligibility decision.
Where it's taking place
- Beijing, Beijing Municipality, China
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Beijing, Beijing Municipality, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.