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New treatment option for Head and Neck Cancer
Official title Thermoradiotherapy for Locally Advanced Head and Neck Cancer Patients
ClinicalTrials.gov ID: NCT06761937
What this study is testing
- What it's testing
- Patients with head and neck cancer treated with radiotherapy (RT) have a substantial change of recurrence of the tumor in the pharynx or lymph nodes in the neck. Once tumor and/or lymph nodes have recurred, the prognosis is poor.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age \>= 18 years
- WHO 0-1
- Mouth opening before treatment of \>= 40 mm for women and \>= 45mm for men
- Squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx proven by cytology / histology.
- Locally advanced disease (stage III-IV).
You likely can't join if
- Patients previously treated by radiation on the same target volume.
- Any condition or circumstance potentially hampering compliance with the follow-up schedule.
- Patients having pacemakers or clustered metal markers (with a total length \>2 cm of metal markers in direct contact).
- Tumor location caudal to a tracheostomy (this prevents penetration of the microwaves to the tumor).
- Anatomical boundaries of the shoulders prohibiting positioning of the applicator.
See the full eligibility criteria
- Age \>= 18 years
- WHO 0-1
- Mouth opening before treatment of \>= 40 mm for women and \>= 45mm for men
- Squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx proven by cytology / histology.
- Locally advanced disease (stage III-IV).
- Curative intend treatment with radiotherapy in the primary setting with a contraindication for systemic adjuvant treatment.
- Ability to understand the requirements of the study and to give written informed consent, as determined by the treating physician.
- Written informed consent.
- Patients previously treated by radiation on the same target volume.
- Any condition or circumstance potentially hampering compliance with the follow-up schedule.
- Patients having pacemakers or clustered metal markers (with a total length \>2 cm of metal markers in direct contact).
- Tumor location caudal to a tracheostomy (this prevents penetration of the microwaves to the tumor).
- Anatomical boundaries of the shoulders prohibiting positioning of the applicator.
The study team makes the final eligibility decision.
Where it's taking place
- Rotterdam, South Holland, Netherlands
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Rotterdam, South Holland, Netherlands. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.