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Compares treatment options for NSCLC
Official title A Study to Evaluate Efficacy, and Safety of QL2107 Plus Chemo and Compare With Keytruda in Participants With IV nqNSCLC
ClinicalTrials.gov ID: NCT06754644
What this study is testing
What is QL2107?
QL2107 is an investigational medicine, being studied as a potential treatment for nsclc.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to compare the efficacy similarities between QL2107 and Keytruda in metastatic non-squamous NSCLC.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- people who voluntarily participate, sign the Informed Consent Form (ICF), and are able to comply with the study procedures;
- people aged ≥ 18 and ≤ 75 years at enrollment, male or female;
- Histologically or cytologically confirmed metastatic (stage IV) non-squamous NSCLC as per the American Joint Committee on Cancer (AJCC) 8th Edition...
- No EGFR sensitive mutations or ALK gene translocations.
- Expected survival ≥ 3 months;
You likely can't join if
- Pulmonary radiation therapy \> 30 Gy within 6 months prior to the first dose;
- Palliative radiation therapy completed within 7 days prior to the first dose;
- Any other form of anti-tumor therapy expected to be required during the study;
- Uncontrolled or symptomatic pericardial effusion, pleural effusion and ascites requiring repeated paracentesis and drainage;
- Presence of metastases to brain stem, meninges and spinal cord or compression;
See the full eligibility criteria
- people who voluntarily participate, sign the Informed Consent Form (ICF), and are able to comply with the study procedures;
- people aged ≥ 18 and ≤ 75 years at enrollment, male or female;
- Histologically or cytologically confirmed metastatic (stage IV) non-squamous NSCLC as per the American Joint Committee on Cancer (AJCC) 8th Edition; if multiple tumor histologies are present, the predominant cell type...
- No EGFR sensitive mutations or ALK gene translocations.
- Expected survival ≥ 3 months;
- Eastern Cooperative Oncology Group (ECOG) performance status score: 0 or 1;
- Pulmonary radiation therapy \> 30 Gy within 6 months prior to the first dose;
- Palliative radiation therapy completed within 7 days prior to the first dose;
- Any other form of anti-tumor therapy expected to be required during the study;
- Uncontrolled or symptomatic pericardial effusion, pleural effusion and ascites requiring repeated paracentesis and drainage;
- Presence of metastases to brain stem, meninges and spinal cord or compression;
The study team makes the final eligibility decision.
Where it's taking place
- Jinan, Shandong, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Jinan, Shandong, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.