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New treatment option for Narcolepsy Type 1
Official title A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
ClinicalTrials.gov ID: NCT06752668
What this study is testing
What is ORX750?
ORX750 is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for narcolepsy type 1.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Narcolepsy Type 1 (NT1), Narcolepsy Type 2 (NT2), and Idiopathic Hypersomnia (IH) are rare conditions that make people feel very sleepy during the day (often referred to as excessive daytime sleepiness [EDS]). People living with these conditions might find it hard to stay alert and pay attention when they are at school, working, driving, or performing other daily activities.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- 18-65 years of age
- BMI ≥17 and ≤37 kg/m2
- Meets the diagnostic criteria of Narcolepsy Type 1 (NT1), Type 2 (NT2) or Idiopathic Hypersomnia (IH) according to ICSD-3-TR criteria
- Is willing and able to discontinue all medications used for the treatment of narcolepsy or idiopathic hypersomnia
- Is willing and able to adhere to additional protocol requirements
You likely can't join if
- A medical disorder other than NT1, NT2, or IH that is associated with excessive daytime sleepiness (EDS).
- Presence of significant cardiovascular, pulmonary, gastrointestinal, hepatic, renal, hematological, malignancy, endocrine, neurological or...
The study team makes the final eligibility decision.
Where it's taking place
- Auburn, Alabama, United States
- Chandler, Arizona, United States
- Scottsdale, Arizona, United States
- Long Beach, California, United States
- Santa Ana, California, United States
- Brandon, Florida, United States
- Miami, Florida, United States
- Orlando, Florida, United States
- Winter Park, Florida, United States
- Atlanta, Georgia, United States
- Riverdale, Georgia, United States
- New Orleans, Louisiana, United States
- Newton, Massachusetts, United States
- Southfield, Michigan, United States
- Sterling Heights, Michigan, United States
- Henderson, Nevada, United States
- Denver, North Carolina, United States
- Huntersville, North Carolina, United States
- Cincinnati, Ohio, United States
- Cleveland, Ohio, United States
+ 14 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Auburn, Alabama, United States; Chandler, Arizona, United States; Scottsdale, Arizona, United States; Long Beach, California, United States; Santa Ana, California, United States; Brandon, Florida, United States and 28 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.