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Official title Influence of Menstrual Cycle Phase on Adaptations to Sprint Interval Training
ClinicalTrials.gov ID: NCT06744517
What this study is testing
- What it's testing
- Sprint interval training improves endurance performance and induces metabolic adaptations in muscle. Most research demonstrating these responses has been conducted in males, with limited studies evaluating changes to endurance performance and skeletal muscle oxidative capacity in females.
- Time commitment: about 2 weeks
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 35, women only
You may be able to join if
- Participating in 150 min of moderate-vigorous physical activity/week
- VO2peak of 'good' or above based on American College of Sport Medicine (ACSM) normative values(greater than 35.0ml/kg/min)
- Body mass index (BMI) between 18-27 kg/m2
- Performing 2-4 structured exercise sessions/week.
- Weight stable (within ± 2kg for at least 6 months)
You likely can't join if
- Hormonal contraceptive use within the last 3 months
- Polycystic ovarian syndrome (PCOS) or endometriosis
- Failure to meet MC verification criteria.
- Diagnosed with cardiovascular or metabolic disease, hyper- or hypogonadism, and/or PCOS
- The use of medication for managing blood glucose or lipid metabolism
- Current use of oral contraceptives or use within the last 3 months
See the full eligibility criteria
- Participating in 150 min of moderate-vigorous physical activity/week
- VO2peak of 'good' or above based on American College of Sport Medicine (ACSM) normative values(greater than 35.0ml/kg/min)
- Body mass index (BMI) between 18-27 kg/m2
- Performing 2-4 structured exercise sessions/week.
- Weight stable (within ± 2kg for at least 6 months)
- Non-smoker
- Menstrual cycle length of 27-35 days
- Minimal menstrual cycle length variability (less than 3 days)
- Ovulating monthly evidenced by a positive urinary luteinizing hormone surge
- Blood progesterone concentration greater than 16 nmol/L.
- Hormonal contraceptive use within the last 3 months
- Polycystic ovarian syndrome (PCOS) or endometriosis
- Failure to meet MC verification criteria.
- Diagnosed with cardiovascular or metabolic disease, hyper- or hypogonadism, and/or PCOS
- The use of medication for managing blood glucose or lipid metabolism
- Current use of oral contraceptives or use within the last 3 months
- Irregular menstrual cycles (\ 35 days)
- Pregnant or post-partum in the last 12 months, lactating or breast feeding within 3 months of the start of study, or menopausal
- Recreational smoking tobacco
- Inability to perform the study exercise protocols or follow the pre-trial dietary or physical activity controls
- Taking medications affecting substrate metabolism (corticosteroids or nSAIDs)
- Actively engaging in a low-carbohydrate diet (e.g., ketogenic, Atkins)
The study team makes the final eligibility decision.
Where it's taking place
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 2 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling female, 18 years to 35 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Toronto, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.