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New treatment option for Vestibular Hypofunction
Official title Subthreshold Vestibular Stimulation as a Strategy for Rehabilitation
ClinicalTrials.gov ID: NCT06732440
What this study is testing
- What it's testing
- The nervous system responds to changes in external or internal conditions by altering the behavior of neurons through multiple forms of neural plasticity. A specific form of plasticity, "homeostatic plasticity", stabilizes neural activity by driving the excitability of neurons toward a "set-point" level of activity.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 19 to 89. Healthy volunteers may be eligible.
You may be able to join if
- for Bilateral Vestibular Hypofunction: 1\. Bilateral lateral canal VOR gain of \< 0.8 on video head impulse testing OR bilateral positive bedside...
- Must be able to stand for 5 minutes unassisted
- No leg or foot amputations
- No lower limb braces
- Not currently pregnant by self-report
You likely can't join if
- for all participants:
- Severe head trauma or traumatic brain injury
- History of seizures
- Alternative neurologic illness or condition known to impact vestibular or balance function (e.g., stroke, neurodegenerative disorders, demyelinating...
- Major psychiatric (e.g., panic disorder, psychosis, etc.) disorder
- Any of the following eye diseases or conditions: amblyopia (or "lazy eye") or history of amblyopia, diagnosis of age- related macular degeneration...
See the full eligibility criteria
- for Bilateral Vestibular Hypofunction: 1\. Bilateral lateral canal VOR gain of \< 0.8 on video head impulse testing OR bilateral positive bedside head impulse test for Unilateral Vestibular Hypofunction: 1\. Unilateral...
- Must be able to stand for 5 minutes unassisted
- No leg or foot amputations
- No lower limb braces
- Not currently pregnant by self-report
- Weight \<= 300 pounds (due to limitations of testing equipment)
- for all participants:
- Severe head trauma or traumatic brain injury
- History of seizures
- Alternative neurologic illness or condition known to impact vestibular or balance function (e.g., stroke, neurodegenerative disorders, demyelinating illness)
- Major psychiatric (e.g., panic disorder, psychosis, etc.) disorder
- Any of the following eye diseases or conditions: amblyopia (or "lazy eye") or history of amblyopia, diagnosis of age- related macular degeneration, retina dystrophy, glaucoma, cataracts,
- Recent (\<6 months) orthopedic injury that may affect test performance
- Recent surgery (\< 6 months) that may impact test performance.
- Other severe health problems (heart disease, pulmonary disease, cancer, etc.) that may affect test performance
- Due to potentially nauseogenic nature of some motions and to protect fetus and mother, pregnant women will also be excluded from this study
- Since the investigators cannot address every possible potential individual recruit in advance, additional exclusion criteria may be required.
The study team makes the final eligibility decision.
Where it's taking place
- Omaha, Nebraska, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 19 years to 89 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Omaha, Nebraska, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.