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Compares treatment options for Contraception
Official title Levonorgestrel-piroxicam Versus Ulipristal Acetate for Emergency Contraception
ClinicalTrials.gov ID: NCT06727734
What this study is testing
What is Levonorgestrel?
Levonorgestrel is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for contraception.
Also referred to as Anlitin.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to compare the failure rate of the levonorgestrel (LNG)-piroxicam combination regimen versus ulipristal acetate (UPA) as emergency contraception (EC). The main questions it aims to answer are: 1.
- Phase 3: a large, late-stage study
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45, women only. Healthy volunteers may be eligible.
You may be able to join if
- women aged 18-45 years;
- requesting an oral EC within 120 hours of a single or the first act of unprotected intercourse in the current menstrual cycle;
- available for follow-up over the next 6 weeks.
You likely can't join if
- post-abortion or postpartum and period have not yet returned,
- being on the following drugs currently: anticoagulants, cyclosporine, tacrolimus, corticosteroids, lithium, serotonin reuptake inhibitors (SSRIs)...
- having unprotected intercourse in this cycle more than 120 hours before attending the clinic,
- being found pregnant at the time of presentation,
- breastfeeding,
- having been sterilized (or partner having been sterilized) or having intrauterine contraceptive device in-situ,
See the full eligibility criteria
- women aged 18-45 years;
- requesting an oral EC within 120 hours of a single or the first act of unprotected intercourse in the current menstrual cycle;
- available for follow-up over the next 6 weeks.
- post-abortion or postpartum and period have not yet returned,
- being on the following drugs currently: anticoagulants, cyclosporine, tacrolimus, corticosteroids, lithium, serotonin reuptake inhibitors (SSRIs), quinolones
- having unprotected intercourse in this cycle more than 120 hours before attending the clinic,
- being found pregnant at the time of presentation,
- breastfeeding,
- having been sterilized (or partner having been sterilized) or having intrauterine contraceptive device in-situ,
- uncertain about the date of the last menstrual period,
- having used a hormonal contraceptive (including EC), progestogen-containing medication or NSAID in the recent one week,
- having history of asthma, urticaria or other allergic reactions to piroxicam, aspirin or other NSAIDs,
- having history of ischaemic heart disease, heart failure, hypertension, cerebrovascular disease or kidney failure requiring dialysis
- having history of peptic ulcer disease and/or gastrointestinal bleeding.
The study team makes the final eligibility decision.
Where it's taking place
- Hong Kong, Hong Kong
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hong Kong, Hong Kong. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.