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New treatment option for Staphylococcus Aureus Bacteraemia
Official title Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia
ClinicalTrials.gov ID: NCT06726395
What this study is testing
What is Penicillin G_1200mg?
Penicillin G_1200mg is an investigational medicine, being studied as a potential treatment for staphylococcus aureus bacteraemia.
Also referred to as bensylpenicillin, benzylpenicillin.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this study is to investigate if benzylpenicillin is a better treatment option than cloxacillin in patients with penicillin-susceptible Staphylococcus aureus bacteraemia.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Aged ≥18 with penicillin susceptible S. aureus bacteraemia (PSSA), and able to provide written informed consent.
You likely can't join if
- allergy to penicillin,
- inability to give informed consent,
- concomitant growth of other clinically significant bacteria in blood cultures
- neutropenia -≥ 96h with prior antibiotics
- When the per oral follow up medication can not be flukloxacillin or penicillinV/Amoxicillin (ie prosthetic joint infection)
- Patients in terminal palliation, where death is expected within 7 days.
See the full eligibility criteria
- Aged ≥18 with penicillin susceptible S. aureus bacteraemia (PSSA), and able to provide written informed consent.
- allergy to penicillin,
- inability to give informed consent,
- concomitant growth of other clinically significant bacteria in blood cultures
- neutropenia -≥ 96h with prior antibiotics
- When the per oral follow up medication can not be flukloxacillin or penicillinV/Amoxicillin (ie prosthetic joint infection)
- Patients in terminal palliation, where death is expected within 7 days.
- Where the treating physician believes cloxacillin is not a first-line treatment.
The study team makes the final eligibility decision.
Where it's taking place
- Lund, Sweden
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Lund, Sweden. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.