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Tests treatment safety and results for HELICOBACTER PYLORI INFECTIONS
Official title Efficacy of Different Durations of Dual and Quadruple Regimens for Helicobacter Pylori Eradication
ClinicalTrials.gov ID: NCT06723197
What this study is testing
What is vonoprazan+amoxicillin?
vonoprazan+amoxicillin is an investigational medicine, being studied as a potential treatment for helicobacter pylori infections.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aimed to compare the efficacy and safety of dual and quadruple regimens with different durations (7-day, 10-day, 14-day) for the eradication of Helicobacter pylori. Subjects were randomized to receive the intervention and were reviewed by 13C-urea breath test after 6 weeks.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70
You may be able to join if
- Patients aged 18-70 years old
- Patients with H.pylori infection (13C/14C-urea breath test)
- Patients without previous treatment for H. pylori eradication
You likely can't join if
- Patients with serious underlying diseases, such as liver insufficiency (Aspartate aminotransferase or alanine aminotransferase greater than the...
- Patients with active gastrointestinal bleeding
- Patients with a history of upper gastrointestinal surgery
- Patients allergic to treatment drugs
- Patients with medication history of bismuth, antibiotics within 4 weeks, or proton pump inhibitor within 2 weeks
- Patients who are pregnant or lactating or unwilling to take contraceptive measures during the trial
See the full eligibility criteria
- Patients aged 18-70 years old
- Patients with H.pylori infection (13C/14C-urea breath test)
- Patients without previous treatment for H. pylori eradication
- Patients with serious underlying diseases, such as liver insufficiency (Aspartate aminotransferase or alanine aminotransferase greater than the normal value), renal insufficiency (Cr≥2.0mg/dL or glomerular filtration...
- Patients with active gastrointestinal bleeding
- Patients with a history of upper gastrointestinal surgery
- Patients allergic to treatment drugs
- Patients with medication history of bismuth, antibiotics within 4 weeks, or proton pump inhibitor within 2 weeks
- Patients who are pregnant or lactating or unwilling to take contraceptive measures during the trial
- Patients with other behaviors that may increase the risk of illness, such as alcohol and drug abuse
- Patients who are unwilling or incapable to provide informed consents
The study team makes the final eligibility decision.
Where it's taking place
- Jinan, Shandong, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Jinan, Shandong, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.