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New treatment option for Critical Illness
Official title Enhanced Protein Intake to Support Muscle Protein Synthesis in ICU
ClinicalTrials.gov ID: NCT06714240
What this study is testing
- What it's testing
- Rationale - Critically ill patients often experience severe skeletal muscle wasting due to an imbalance between muscle protein synthesis (MPS) and degradation, contributing to long-term impairments such as ICU-acquired weakness (ICU-AW) and post-intensive care syndrome (PICS). Effective interventions to mitigate muscle wasting remain a critical unmet need.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Aged ≥ 18 years
- Suitability for enteral nutrition (i.e., no GI failure, absence of complete intestinal obstruction, no major intra-abdominal sepsis)
- Expected mechanical ventilation of minimal three days
- Expected ICU stay of at least seven days
You likely can't join if
- BMI ≥ 40 kg/m²
- Spinal cord injury
- Chronic corticosteroid use before hospital admission
- severe allergies or intolerances (e.g., to cow's milk protein, fish, soy, pea protein or galactosemia)
- Severe kidney and/or liver failure
- Requirements for dialysis
See the full eligibility criteria
- Aged ≥ 18 years
- Suitability for enteral nutrition (i.e., no GI failure, absence of complete intestinal obstruction, no major intra-abdominal sepsis)
- Expected mechanical ventilation of minimal three days
- Expected ICU stay of at least seven days
- BMI ≥ 40 kg/m²
- Spinal cord injury
- Chronic corticosteroid use before hospital admission
- severe allergies or intolerances (e.g., to cow's milk protein, fish, soy, pea protein or galactosemia)
- Severe kidney and/or liver failure
- Requirements for dialysis
- Bleeding disorders, including anticoagulant and antiplatelet therapy
The study team makes the final eligibility decision.
Where it's taking place
- Hasselt, Limburg, Belgium
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hasselt, Limburg, Belgium. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.