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Tests treatment safety and results for Clinical Efficacy of Submucosal Dexamethasone and Oral...
Official title Comparison of Clinical Efficacy of Submucosal Dexamethasone and Oral Trypsin-chymotrypsin for Reduction of Postoperative Sequelae After Lower Third Molar Surgery
ClinicalTrials.gov ID: NCT06713733
What this study is testing
What is Dexamethasone?
Dexamethasone is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for clinical efficacy of submucosal dexamethasone and oral trypsin chymotrypsin for reduction of postoperative sequelae after lower third molar surgery.
Also referred to as submucosal dexamethasone.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Pain, edema and trismus are the most frequent postoperative sequelae to surgical removal of impacted teeth, all of are due to the local inflammatory response. Use of corticosteroids decrease tissue mediators of inflammation and reduce edema.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- Clinically healthy patients (ASA I) patient free of any systemic diseases that could interfere with wound healing or surgical operation.
- Free of any recent anti-inflammatory drug intake or being under long term treatment with medicaments that will obscure the assessment of the...
- Free from allergy to the drugs used in the study
- Patients requiring surgical removal of the mandibular impacted third molar
You likely can't join if
- Patients who are ASA II to ASA VI.
- Patients already on corticosteroids through any route.
- Patients with known allergy to any drugs.
- Pregnant and lactating females
- Patient not consenting to participate in the study
The study team makes the final eligibility decision.
Where it's taking place
- Dharān, Koshi, Nepal
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Dharān, Koshi, Nepal. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.