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New treatment option for Esophageal Cancer
Official title Effect of Premedication With Pronase on Mucosal Cleanliness During EGD
ClinicalTrials.gov ID: NCT06713421
What this study is testing
What is Dimethicone+Pronase?
Dimethicone+Pronase is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for esophageal cancer.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Gastric cancer and esophageal cancer are common malignant tumors that threaten people's life and health. Esophagogastroduodenoscopy (EGD) is an important tool for screening upper gastrointestinal tumors, especially early tumors, and an effective method for detecting other upper gastrointestinal lesions, including ulcers and polyps.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70. Healthy volunteers may be eligible.
You may be able to join if
- Male or female aged ≥18 years and ≤70 years;
- Voluntarily participate in the trial and sign the informed consent.
You likely can't join if
- active gastrointestinal bleeding;
- esophageal stricture, complete pyloric obstruction and gastroparesis caused by various reasons;
- diagnosed malignant tumors of the upper digestive tract;
- a history of upper gastrointestinal surgery;
- severe heart, liver and kidney diseases, and the doctor judges that it is not suitable for painless gastroscopy;
- serious mental illness;
See the full eligibility criteria
- Male or female aged ≥18 years and ≤70 years;
- Voluntarily participate in the trial and sign the informed consent.
- active gastrointestinal bleeding;
- esophageal stricture, complete pyloric obstruction and gastroparesis caused by various reasons;
- diagnosed malignant tumors of the upper digestive tract;
- a history of upper gastrointestinal surgery;
- severe heart, liver and kidney diseases, and the doctor judges that it is not suitable for painless gastroscopy;
- serious mental illness;
- pregnancy or breastfeeding;
- an allergy to pronase or dimeticone;
- current participation in other clinical trials and in the follow-up or drug washout period;
- patients considered by the investigator to be unsuitable for this study
The study team makes the final eligibility decision.
Where it's taking place
- Shanghai, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shanghai, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.