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New treatment option for Elective Surgical Patient
Official title Effect of Dexmedetomidine on Hemodynamic Response to Endotracheal Intubation in Hypertensive Patients
ClinicalTrials.gov ID: NCT06712186
What this study is testing
What is Dexmedetomidine Group / Group D?
Dexmedetomidine Group / Group D is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for elective surgical patient.
Also referred to as Dexemeditomidine.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Dexmedetomidine, an alpha-2 adrenergic agonist, has been shown to provide several benefits during endotracheal intubation: 1. \_Reduced anxiety and stress\_: Dexmedetomidine's anxiolytic and sedative effects help reduce anxiety and stress associated with endotracheal intubation.
- Phase 2: a mid-size study of how well it works
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 and older
You may be able to join if
- ASA Grade II
- Age \> 60 years
- Elective surgical procedures under GA.
- All patients with a diagnosis of hypertension for 6 months or more and undergoing treatment with antihypertensive medications.
You likely can't join if
- Patient refusal
- ASA Grade III and IV
- Severely Hypovolemic state
- Emergency surgeries
- Body weight more than 20% of ideal body weight.
- Patients with known or unanticipated difficult intubation and those requiring more than 15 sec or two attempts at laryngoscopy
See the full eligibility criteria
- ASA Grade II
- Age \> 60 years
- Elective surgical procedures under GA.
- All patients with a diagnosis of hypertension for 6 months or more and undergoing treatment with antihypertensive medications.
- Patient refusal
- ASA Grade III and IV
- Severely Hypovolemic state
- Emergency surgeries
- Body weight more than 20% of ideal body weight.
- Patients with known or unanticipated difficult intubation and those requiring more than 15 sec or two attempts at laryngoscopy
- Allergic to dexmedetomidine
- Non complaint hypertensive patients
- Patients with uncontrolled hypertension.
The study team makes the final eligibility decision.
Where it's taking place
- Karachi, Sindh, Pakistan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Karachi, Sindh, Pakistan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.