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New treatment option for Knee
Official title Amniotic Suspension Allograft Injection for Knee Osteoarthritis
ClinicalTrials.gov ID: NCT06704893
What this study is testing
What is ASA injection 40 mg group?
ASA injection 40 mg group is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for knee.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- There have been few clinical trials on ASA for the treatment of knee osteoarthritis, and there is currently no literature reporting the optimal treatment dosage. Non-surgical treatment options include braces, weight loss, lifestyle changes, oral pain relievers, and intra-articular injections.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Age between 18 and 80 years.
- Body mass index (BMI) less than 40 kg/m².
- Symptomatic knee osteoarthritis with X-ray evidence graded 2 or 3 on the Kellgren-Lawrence (KL) grading scale.
- Numerical Rating Scale (NRS) score (scale 1 to 10) for pain greater than 4 over the past 7 days.
- Able to walk independently or with the aid of a cane.
You likely can't join if
- Pregnant women or women planning pregnancy.
- Regular use of anticoagulants.
- Use of pain medications (except acetaminophen) within 15 days prior to injection.
- History of substance abuse.
- Patients who take additional knee symptom-relief medications during the study must report it to the research team; failure to comply will result in...
- Corticosteroid or visco-supplementation injection into the affected knee within 3 months prior to enrollment.
See the full eligibility criteria
- Age between 18 and 80 years.
- Body mass index (BMI) less than 40 kg/m².
- Symptomatic knee osteoarthritis with X-ray evidence graded 2 or 3 on the Kellgren-Lawrence (KL) grading scale.
- Numerical Rating Scale (NRS) score (scale 1 to 10) for pain greater than 4 over the past 7 days.
- Able to walk independently or with the aid of a cane.
- Pregnant women or women planning pregnancy.
- Regular use of anticoagulants.
- Use of pain medications (except acetaminophen) within 15 days prior to injection.
- History of substance abuse.
- Patients who take additional knee symptom-relief medications during the study must report it to the research team; failure to comply will result in exclusion.
- Corticosteroid or visco-supplementation injection into the affected knee within 3 months prior to enrollment.
- Knee surgery on the affected side within 12 months before enrollment, or surgery on the contralateral knee within 6 months before enrollment. 9\. History of organ or hematopoietic stem cell transplant. 11. Current use...
The study team makes the final eligibility decision.
Where it's taking place
- Kaohsiung, Taiwan, Taiwan
- Kaohsiung City, Taiwan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Kaohsiung, Taiwan, Taiwan; Kaohsiung City, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.