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New treatment option for Spinal Cord Injury
Official title Improving 24-hour Blood Pressure Stability in Spinal Cord Injury With Low Oxygen Therapy
ClinicalTrials.gov ID: NCT06691165
What this study is testing
What is Low oxygen therapy (LOT)?
Low oxygen therapy (LOT) is an investigational medicine, given as an once-daily, being studied as a potential treatment for spinal cord injury.
Also referred to as Intermittent hypoxia.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study examines the effects of low oxygen therapy (LOT) on the stability of 24-hour blood pressure in persons with chronic cervical spinal cord injury. This study will examine if brief episodes of breathing lower oxygen, termed low oxygen therapy (LOT), which has been shown to enhance autonomic nervous system activity, can improve blood pressure stability in individuals with spinal cord injury.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 19 to 65
You may be able to join if
- Are between the ages of 19-65
- Living with a chronic cervical (at or above T1) spinal cord injury of at least one year
- Are fluent in english
You likely can't join if
- High-cervical injuries requiring ventilator assistance to breathe will be excluded on account of the necessity of the facemask for the delivery of...
- Unhealed fracture, contracture, or pressure sore that might interfere with participants' ability to complete the protocol
- Additional concurrent neurological conditions (e.g., multiple sclerosis, Parkinson disease, stroke or brain injury)
- Uncontrolled cardiovascular or pulmonary disease
- Severe neuropathic pain
- Severe recurrent autonomic dysreflexia
See the full eligibility criteria
- Are between the ages of 19-65
- Living with a chronic cervical (at or above T1) spinal cord injury of at least one year
- Are fluent in english
- High-cervical injuries requiring ventilator assistance to breathe will be excluded on account of the necessity of the facemask for the delivery of hypoxia
- Unhealed fracture, contracture, or pressure sore that might interfere with participants' ability to complete the protocol
- Additional concurrent neurological conditions (e.g., multiple sclerosis, Parkinson disease, stroke or brain injury)
- Uncontrolled cardiovascular or pulmonary disease
- Severe neuropathic pain
- Severe recurrent autonomic dysreflexia
- History of seizure disorders
- Known pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Kelowna, British Columbia, Canada
- Vancouver, British Columbia, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 19 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Kelowna, British Columbia, Canada; Vancouver, British Columbia, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.