BridgeMD
New treatment option for Obesity and Overweight
Official title Intermittent Carbohydrate Restriction in Cardiometabolic Health
ClinicalTrials.gov ID: NCT06684834
What this study is testing
- What it's testing
- Metabolic conditions, such as heart disease, type 2 diabetes, and metabolic syndrome, are among the leading causes of disability and mortality worldwide. Identifying innovative lifestyle strategies to reduce metabolic risk remains a public health priority.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65. Healthy volunteers may be eligible.
You may be able to join if
- Waist circumference of ≥94 cm (37 inches) if male and ≥80 cm (31.5 inches) if female, or BMI above 25 kg/m2
- Fat mass index (FMI) of \>6 kg/m2 for males, and \>9 kg/m2 for females
- Aged between 18-65 years
- Has maintained a stable weight in the last three months (\<3% change in body mass)
- Keeps track of menstrual cycle regularity or oral contraceptive use (females only)
You likely can't join if
- Has a body weight of ≥120kg
- Plans to undertake other lifestyle modifications during the study to manage weight (e.g. changes in dietary intake or activity levels)
- Current or previous eating disorder
- Diagnosed with major chronic conditions (e.g. type 2 diabetes, coronary heart disease, cancer, chronic kidney disease, etc.)
- Use of medication that may interfere with study outcomes (e.g. glucose or lipid lowering medications)
- Currently or recently pregnant (within last 6 months), planning to get pregnant or currently lactating
See the full eligibility criteria
- Waist circumference of ≥94 cm (37 inches) if male and ≥80 cm (31.5 inches) if female, or BMI above 25 kg/m2
- Fat mass index (FMI) of \>6 kg/m2 for males, and \>9 kg/m2 for females
- Aged between 18-65 years
- Has maintained a stable weight in the last three months (\<3% change in body mass)
- Keeps track of menstrual cycle regularity or oral contraceptive use (females only)
- Has a body weight of ≥120kg
- Plans to undertake other lifestyle modifications during the study to manage weight (e.g. changes in dietary intake or activity levels)
- Current or previous eating disorder
- Diagnosed with major chronic conditions (e.g. type 2 diabetes, coronary heart disease, cancer, chronic kidney disease, etc.)
- Use of medication that may interfere with study outcomes (e.g. glucose or lipid lowering medications)
- Currently or recently pregnant (within last 6 months), planning to get pregnant or currently lactating
- Has donated more than 500ml of blood in the last 3 months prior to the initial laboratory visit
- Insufficient mental capacity or language skills to independently understand and follow the study protocol
- Dietary restrictions to ingredients in test meals (e.g. gluten and lactose)
- Has an irregular sleeping pattern (e.g. due to undertaking night-shift work)
- Any condition, concurrent intervention or behaviour deemed either to pose undue personal risk to the participant or to introduce bias into the experiment
The study team makes the final eligibility decision.
Where it's taking place
- Bath, Somerset, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bath, Somerset, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.