BridgeMD
New treatment option for Pediatric Acute Respiratory Distress Syndrome
Official title Pediatric Positive End Expiratory Pressure (PEEP) Titration Using Electrical Impedence Tomography (EIT)
ClinicalTrials.gov ID: NCT06684119
What this study is testing
- What it's testing
- The goal of this clinical trial is to perform a PEEP titration protocol and use EIT to identify the optimal PEEP at which lung overdistention and collapse are most effectively balanced. The primary and secondary aims of the study are as follows: Identify the difference between the optimal PEEP recommended by EIT metrics and the current guideline recommended approach to identifying optimal PEEP in PARDS.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 0 to 18
You may be able to join if
- Any person who is less than 18 years of age
- is on invasive mechanical ventilation
- is not spontaneously breathing
- meets PARDS criteria
You likely can't join if
- Contraindication to the use of EIT
- Hemodynamic instability
- Contraindications to hypercapnia
- patients with uncuffed endotracheal or tracheostomy tubes
- diagnosis of pneumothorax or bronchopleural fistula
- non-conventional ventilation
See the full eligibility criteria
- Any person who is less than 18 years of age
- is on invasive mechanical ventilation
- is not spontaneously breathing
- meets PARDS criteria
- Contraindication to the use of EIT
- Hemodynamic instability
- Contraindications to hypercapnia
- patients with uncuffed endotracheal or tracheostomy tubes
- diagnosis of pneumothorax or bronchopleural fistula
- non-conventional ventilation
- any patient on extra-corporeal membrane oxygenation (ECMO) support
- less than 1 week post-operatively from cardiac surgery
- the following cardiac diagnoses: Glenn or Fontan physiology, significant right to left shunt
- Corrected Gestational Age \< 37 weeks
- pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Los Angeles, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 0 years to 18 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Los Angeles, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.