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New treatment option for Stroke
Official title Explore the Effects of Cortical Priming on Visuomotor Stepping Learning in Persons With Chronic Stroke
ClinicalTrials.gov ID: NCT06681207
What this study is testing
What is anodal transcranial direct current stimulation (a-tDCS)?
anodal transcranial direct current stimulation (a-tDCS) is an investigational medicine, being studied as a potential treatment for stroke.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This research study aims to understand the relationship between brain stimulation and leg skill learning in both healthy adults and persons with chronic stroke.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 90. Healthy volunteers may be eligible.
You may be able to join if
- Age between 21 and 90 years
- Medical history of a unilateral stroke occurring ≥ 6 months prior to enrollment
- MRI or CT evidence from the imaging report shown that the stroke involves the corticospinal tract
- Hemiparesis involving the lower extremity (Fulg-Meyer LE motor test)
- No passive range of motion limitation in bilateral hips and knees
You likely can't join if
- Pregnant women
- MRI or CT evidence of involvement of the basal ganglia or cerebellum, evidence of multiple lesions, or evidence of any other brain damage or...
- Have any metal implants, cardiac pacemakers, or history of seizures
- Ongoing orthopedic or other neuromuscular disorders that will restrict exercise training
- Any vestibular dysfunction or unstable angina
- Significant cognitive deficits (inability to follow a 2-step command) or severe receptive or global aphasia\
See the full eligibility criteria
- Age between 21 and 90 years
- Medical history of a unilateral stroke occurring ≥ 6 months prior to enrollment
- MRI or CT evidence from the imaging report shown that the stroke involves the corticospinal tract
- Hemiparesis involving the lower extremity (Fulg-Meyer LE motor test)
- No passive range of motion limitation in bilateral hips and knees
- Limitation of ankle passive range of motion to 10 degrees of dorsiflexion or less
- Visual acuity can be corrected by glasses or contact lens to 20/20
- Able to walk independently with/without assistant devices for 10 meters
- Able to maintain standing position without any assistance \> 30 sec (Short Physical Performance Battery)
- Evaluation of cognitive status: Mini-mental status examination (MMSE) score ≥ 24
- Pregnant women
- MRI or CT evidence of involvement of the basal ganglia or cerebellum, evidence of multiple lesions, or evidence of any other brain damage or malignant neoplasm or tumors
- Have any metal implants, cardiac pacemakers, or history of seizures
- Ongoing orthopedic or other neuromuscular disorders that will restrict exercise training
- Any vestibular dysfunction or unstable angina
- Significant cognitive deficits (inability to follow a 2-step command) or severe receptive or global aphasia\
The study team makes the final eligibility decision.
Where it's taking place
- Galveston, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 90 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Galveston, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.