BridgeMD
New treatment option for Irritable Bowel Syndrome (IBS)
Official title Irritable Bowel Syndrome and Control Volunteers: Diet Challenge
ClinicalTrials.gov ID: NCT06668922
What this study is testing
- What it's testing
- The study will investigate the relationship between fecal bile acids, short-chain fatty acids (SCFAs), and the gut microbiota in irritable bowel syndrome (IBS). The central hypothesis of this study is that specific shifts in the GI microbiome composition correlate with altered colonic SCFAs and BAs and contribute to IBS symptoms.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 17 to 65. Healthy volunteers may be eligible.
You may be able to join if
- Age 18-75
- Individuals with irritable bowel syndrome (IBS)
- Healthy volunteers (healthy controls) with no prior history of gastrointestinal (GI) disease or symptoms
- No dietary restrictions other than vegetarian
You likely can't join if
- Inflammatory bowel disease, celiac disease, or certain types of abdominal cancer, as well as those with thyroid or liver issues
- Abdominal surgery or abdominal radiation within 6 months of study participation, with an exception for C-section or gallbladder removal
- Use of any prescription, over the counter, or herbal medications known to affect gastrointestinal function or study interpretation, such as opioids...
- An exception will be permitted for limited use of stable low doses of antidepressants for individuals who have been taking them for a period greater...
- Rescue medication such as Bisacodyl (dulcolax) to relieve severe constipation and allow for stool collection will be permitted when needed.
- Use of Ozempic and Ozempic-type medications
See the full eligibility criteria
- Age 18-75
- Individuals with irritable bowel syndrome (IBS)
- Healthy volunteers (healthy controls) with no prior history of gastrointestinal (GI) disease or symptoms
- No dietary restrictions other than vegetarian
- Inflammatory bowel disease, celiac disease, or certain types of abdominal cancer, as well as those with thyroid or liver issues
- Abdominal surgery or abdominal radiation within 6 months of study participation, with an exception for C-section or gallbladder removal
- Use of any prescription, over the counter, or herbal medications known to affect gastrointestinal function or study interpretation, such as opioids, inflammatory drugs or certain antidepressants, within 6 months prior...
- An exception will be permitted for limited use of stable low doses of antidepressants for individuals who have been taking them for a period greater than one month.
- Rescue medication such as Bisacodyl (dulcolax) to relieve severe constipation and allow for stool collection will be permitted when needed.
- Use of Ozempic and Ozempic-type medications
- Pregnant or breastfeeding women
- Antibiotic use within 3 months of study participation
- Use of prebiotics or probiotics within the 2 weeks before the study initiation
- Regular tobacco use within the past 6 months
The study team makes the final eligibility decision.
Where it's taking place
- Los Angeles, California, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 17 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Los Angeles, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.