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New treatment option for Relatively Healthy Volunteers
Official title Daily Intake of Multivitamin & Mineral Supplementation Effects on Biological Age of Relatively Healthy Middle-aged Individuals
ClinicalTrials.gov ID: NCT06666660
What this study is testing
- What it's testing
- Micronutrients, such as vitamins and minerals, are required to sustain fundamental physiological processes in individuals. As individuals age, the risk of having suboptimal levels of micronutrients increases due to several age-related changes affecting their digestion and assimilation processes.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 to 60. Healthy volunteers may be eligible.
You may be able to join if
- Participants will be recruited if they fall in the following categories:
- Relatively healthy middle aged (40-60 years) man or woman;
- Completed the pre-screening requirements and has managed to schedule the screening visit;
- Met the randomization criteria after the screening visit i.e., your biological age (as measured by blood DNA methylation) is greater than the...
- Able to attend all 4 research visits for screening and research data collection at the NUHS Centre for Healthy Longevity (CHL) at Alexandra Hospital...
You likely can't join if
- Participants will NOT be recruited if they fall in any one or more of the following categories:
- BMI lower than 18 kg/m2 or higher than or equal to 30 kg/m2 [25];
- Pre-existing, or history of major cardiovascular diseases (coronary artery disease, heart failure, stroke, peripheral vascular disease, pulmonary...
- Type 1 diabetes and Type 2 diabetes;
- Active cancer or treatment of cancer in the last 3 years;
- Chronic obstructive pulmonary disease (COPD), severe asthma (taking daily medications);
See the full eligibility criteria
- Participants will be recruited if they fall in the following categories:
- Relatively healthy middle aged (40-60 years) man or woman;
- Completed the pre-screening requirements and has managed to schedule the screening visit;
- Met the randomization criteria after the screening visit i.e., your biological age (as measured by blood DNA methylation) is greater than the chronological age;
- Able to attend all 4 research visits for screening and research data collection at the NUHS Centre for Healthy Longevity (CHL) at Alexandra Hospital or MD11, National University of Singapore.
- Willing to wear an OURA ring for 14 consecutive days after each study visits.
- Willing to download study platform application into their mobile phone throughout the study period.
- Participants will NOT be recruited if they fall in any one or more of the following categories:
- BMI lower than 18 kg/m2 or higher than or equal to 30 kg/m2 [25];
- Pre-existing, or history of major cardiovascular diseases (coronary artery disease, heart failure, stroke, peripheral vascular disease, pulmonary hypertension), severe/uncontrolled hypertension (more than 1 prescribed...
- Type 1 diabetes and Type 2 diabetes;
- Active cancer or treatment of cancer in the last 3 years;
- Chronic obstructive pulmonary disease (COPD), severe asthma (taking daily medications);
- Pregnant women or women planning pregnancy in the next 12 months;
- Multiple sclerosis or autoimmune/immune deficiency diseases such as Rheumatic arthritis, HIV, Crohn's disease;
- Recent history of sepsis or infection (within 3 months of in-patient hospitalisation);
- Any psychiatric disease or neurodegenerative diseases such as Alzheimer's Disease, Parkinson's Disease, Lewy body dementia, and any eating disorders;
- Hepatitis and liver cirrhosis (independent of severity);
- Severe kidney disease (GFR less than 30 ml/min/1.73 m2);
- Skin disease (on systemic medication);
- Individuals who are on another trial that requires them taking similar or partially similar investigational product (Appendix 1);
- Individuals who are advised by their medical practitioner to take a MVM supplement;
- Refuse to stop taking any non-prescribed supplements that contain the investigational product (Appendix 1) within one month before the screening visit and during the study period;
- Taking a medically prescribed supplements that contains 2 or more of the ingredients of the investigational product (Appendix 1);
- Individuals with planned hospitalization in the next 12 months;
- Any serious medical illness which in the PI's judgment may jeopardise the participant by his or her participation in this study or may hamper his or her ability to perform and complete procedures required in the study.
The study team makes the final eligibility decision.
Where it's taking place
- Singapore, Singapore, Singapore
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Singapore, Singapore, Singapore. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.