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New treatment option for Myocardial Infarct
Official title Heart Attack Blood Oxygen Therapy Trial
ClinicalTrials.gov ID: NCT06662890
What this study is testing
- What it's testing
- 'Heart attack', known as acute ST-segment elevation myocardial infarction, is a leading cause of heart failure and death. A lack of blood and oxygen damages the heart muscle potentially causing heart failure and premature death.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥18 years.
- Ischemic time ≤6 hours from symptom onset
- Acute anterior ST-segment elevation myocardial infarction
- Infarct-related left anterior descending coronary artery TIMI flow grade 2-3 at the end of PCI
- Radial artery access
You likely can't join if
- Proximal coronary artery stenosis that restricts blood flow with the SSO2 catheter in place
- Post-PCI non-stented dissection or perforation.
- Moderate - severe heart valve stenosis, insufficiency, pericardial disease, or non-ischaemic cardiomyopathy
- Known pregnancy.
- Cardiogenic shock
- Contra-indication to anticoagulation
See the full eligibility criteria
- Age ≥18 years.
- Ischemic time ≤6 hours from symptom onset
- Acute anterior ST-segment elevation myocardial infarction
- Infarct-related left anterior descending coronary artery TIMI flow grade 2-3 at the end of PCI
- Radial artery access
- Partial pressure of oxygen (PaO2) \>80 mmHg (10.7 kPa)
- Proximal coronary artery stenosis that restricts blood flow with the SSO2 catheter in place
- Post-PCI non-stented dissection or perforation.
- Moderate - severe heart valve stenosis, insufficiency, pericardial disease, or non-ischaemic cardiomyopathy
- Known pregnancy.
- Cardiogenic shock
- Contra-indication to anticoagulation
- Acute mechanical complication e.g., ventricular septal rupture, pseudoaneurysm, mitral regurgitation
- Hemoglobin \<10 g/dL
- Major bleeding or major surgery within the past two months
- Contra-indication to cardiovascular magnetic resonance (CMR) imaging e.g., severe claustrophobia, metallic foreign body.
- Lack of witness verbal consent.
The study team makes the final eligibility decision.
Where it's taking place
- Clydebank, Dunbartonshire, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Clydebank, Dunbartonshire, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.