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New treatment option for Insomnia
Official title Optimizing the Timing of rTMS to Enhance the Administration of Insomnia Treatment
ClinicalTrials.gov ID: NCT06656533
What this study is testing
- What it's testing
- Repetitive transcranial magnetic stimulation (rTMS) has shown to be a promising technique for improving insomnia symptoms and sleep quality. However, the impact of circadian rhythmicity on rTMS sessions and its potential influence on insomnia therapy remains unclear.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 25 to 45
You may be able to join if
- Males and females of any racial or ethnic group, aged 25-45 (inclusive)
- Insomnia diagnosis via the DUKE
- Fluent and literate in English
- Written, informed consent
- Reside within 60 miles of Stanford University
You likely can't join if
- Presence of other sleep or circadian rhythm disorders that significantly contribute to their sleep disturbance. The presence of these disorders will...
- No regular use of benzodiazepine, opiate, thyroid, anticonvulsant or antipsychotic medications
- Use of psychotropic medications that would significantly impact sleep, alertness, and no illicit drugs.
- Excessive alcohol consumption (\>14 drinks per week or \> 4 drinks per occasion)
- Presence of suicidal ideations representing elevated risk as determined by the Beck Depression Inventory (score of \> 0 on BDI question #9).
- History of neurological or cardiovascular disorders, brain surgery, electroconvulsive or radiation treatment, brain hemorrhage or tumor, stroke...
See the full eligibility criteria
- Males and females of any racial or ethnic group, aged 25-45 (inclusive)
- Insomnia diagnosis via the DUKE
- Fluent and literate in English
- Written, informed consent
- Reside within 60 miles of Stanford University
- Presence of other sleep or circadian rhythm disorders that significantly contribute to their sleep disturbance. The presence of these disorders will be assessed by the DUKE structured interview for sleep disorders.
- No regular use of benzodiazepine, opiate, thyroid, anticonvulsant or antipsychotic medications
- Use of psychotropic medications that would significantly impact sleep, alertness, and no illicit drugs.
- Excessive alcohol consumption (\>14 drinks per week or \> 4 drinks per occasion)
- Presence of suicidal ideations representing elevated risk as determined by the Beck Depression Inventory (score of \> 0 on BDI question #9).
- History of neurological or cardiovascular disorders, brain surgery, electroconvulsive or radiation treatment, brain hemorrhage or tumor, stroke, seizures or epilepsy, diabetes, hypo- or hyperthyroidism, head trauma with...
- Substance abuse or dependence
- History of significant head trauma followed by persistent neurologic deficits or known structural brain abnormalities OR traumatic brain injury in the past two months
- Severe impediment to vision, hearing and/or hand movement, likely to interfere with the ability to complete the assessments, or are unable and/or unlikely to follow the study protocols
- Pregnant or breast feeding
- Current or lifetime history of bipolar disorder, PTSD or psychosis or current depression
- Received cognitive behavioral therapy for insomnia within the past year
- Current exposure to trauma, or exposure to trauma within the past 3 months
- Working a rotating shift that overlaps with 2400h
- Individuals who were high risk for sleep apnea on the Berlin Questionnaire and are not CPAP adherent
- Participants with a current psychiatric disorder who are also on medications that significantly increase the risk of seizure. The antidepressants clomipramine, bupropion, maprotiline will be excluded because they are...
The study team makes the final eligibility decision.
Where it's taking place
- Palo Alto, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 25 years to 45 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Palo Alto, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.