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Tests treatment safety and results for Paronychia
Official title Efficacy and Safety of Add-on Timolol for EGFR-TKI and ALK-TKI Induced Paronychia
ClinicalTrials.gov ID: NCT06643416
What this study is testing
What is Timolol 0.5% eye drops and betamethasone valerate 0.1% cream?
Timolol 0.5% eye drops and betamethasone valerate 0.1% cream is an investigational medicine, given as an once-daily infusion into a vein, being studied as a potential treatment for paronychia.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- To assess the clinical efficacy of add-on topical timolol 0.5% eye drops to betamethasone valerate 0.1% for the treatment of EGFR-TKI and ALK-TKI induced paronychia.
- Phase 3: a large, late-stage study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Aged 18 years or above, either males or females.
- Received EGFR-TKI and ALK-TKI, namely gefitinib, erlotinib, afatinib, osimertinib, amivantamab, dacomitinib, mobocertinib, crizotinib, ceritinib...
- Paronychia (fingernails, toenails, or both) as an adverse event from EGFR-TKI use
- Written informed consent obtained from patient
- people are diagnosed with advanced non-small cell lung cancer
You likely can't join if
- 1\. Age below18
- 2\. Patients who are allergic to, or contraindicated to topical timolol use
- 3\. Pregnant women or nursing mother
- 4\. Non-consenting patients
- 5\. people are not diagnosed with advanced non-small cell lung cancer
The study team makes the final eligibility decision.
Where it's taking place
- Hong Kong, Hong Kong
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hong Kong, Hong Kong. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.